| Reaction Details |
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 | Report a problem with these data |
| Target | Dual specificity protein kinase CLK3 |
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| Ligand | BDBM181050 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Kinase Inhibition Assay |
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| IC50 | 346±0.0 nM |
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| Citation |  Prak, K; Kriston-Vizi, J; Chan, AW; Luft, C; Costa, JR; Pengo, N; Ketteler, R Benzobisthiazoles Represent a Novel Scaffold for Kinase Inhibitors of CLK Family Members. Biochemistry55:608-17 (2016) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Dual specificity protein kinase CLK3 |
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| Name: | Dual specificity protein kinase CLK3 |
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| Synonyms: | CDC2-like kinase 3 (CLK3) | CLK3 | CLK3_HUMAN | Dual specificity protein kinase CLK3 |
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| Type: | Protein |
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| Mol. Mass.: | 73570.11 |
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| Organism: | Homo sapiens (Human) |
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| Description: | n/a |
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| Residue: | 638 |
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| Sequence: | MPVLSARRRELADHAGSGRRSGPSPTARSGPHLSALRAQPARAAHLSGRGTYVRRDTAGG
GPGQARPLGPPGTSLLGRGARRSGEGWCPGAFESGARAARPPSRVEPRLATAASREGAGL
PRAEVAAGSGRGARSGEWGLAAAGAWETMHHCKRYRSPEPDPYLSYRWKRRRSYSREHEG
RLRYPSRREPPPRRSRSRSHDRLPYQRRYRERRDSDTYRCEERSPSFGEDYYGPSRSRHR
RRSRERGPYRTRKHAHHCHKRRTRSCSSASSRSQQSSKRSSRSVEDDKEGHLVCRIGDWL
QERYEIVGNLGEGTFGKVVECLDHARGKSQVALKIIRNVGKYREAARLEINVLKKIKEKD
KENKFLCVLMSDWFNFHGHMCIAFELLGKNTFEFLKENNFQPYPLPHVRHMAYQLCHALR
FLHENQLTHTDLKPENILFVNSEFETLYNEHKSCEEKSVKNTSIRVADFGSATFDHEHHT
TIVATRHYRPPEVILELGWAQPCDVWSIGCILFEYYRGFTLFQTHENREHLVMMEKILGP
IPSHMIHRTRKQKYFYKGGLVWDENSSDGRYVKENCKPLKSYMLQDSLEHVQLFDLMRRM
LEFDPAQRITLAEALLHPFFAGLTPEERSFHTSRNPSR
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| BDBM181050 |
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| n/a |
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| Name | BDBM181050 |
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| Synonyms: | 3A5 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H10N4OS3 |
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| Mol. Mass. | 382.482 |
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| SMILES | Cc1nc2ccc3sc(NC(=O)c4ccc5ncsc5c4)nc3c2s1 |
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| Structure | 
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