| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A1 |
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| Ligand | BDBM633489 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Human Adenosine A2A Receptor Binding Assay |
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| Ki | <20±n/a nM |
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| Citation |  Kim, K; Kim, J; Moon, A; Song, D; Lee, Y; Jung, J Prevention and/or treatment of CNS disorders US Patent US11806350 Publication Date 11/7/2023 |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A1 |
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| Name: | Adenosine receptor A1 |
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| Synonyms: | A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 36520.92 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P30542 |
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| Residue: | 326 |
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| Sequence: | MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPAPPIDEDLPEERPDD
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| BDBM633489 |
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| n/a |
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| Name | BDBM633489 |
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| Synonyms: | 3-(6-amino-1-(4-amino-2,6-difluorobenzyl)-1H-pyrazolo[3,4-d]pyrimidine-4-yl)benzonitrile | US11806350, Compound 207 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H13F2N7 |
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| Mol. Mass. | 377.3502 |
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| SMILES | Nc1cc(F)c(Cn2ncc3c(nc(N)nc23)-c2cccc(c2)C#N)c(F)c1 |
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| Structure | 
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