| Reaction Details |
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 | Report a problem with these data |
| Target | Adenosine receptor A2a |
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| Ligand | BDBM633503 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Human Adenosine A1 Receptor Binding Assay |
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| Ki | <100±n/a nM |
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| Citation |  Kim, K; Kim, J; Moon, A; Song, D; Lee, Y; Jung, J Prevention and/or treatment of CNS disorders US Patent US11806350 Publication Date 11/7/2023 |
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| More Info.: | Get all data from this article, Assay Method |
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| Adenosine receptor A2a |
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| Name: | Adenosine receptor A2a |
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| Synonyms: | A2A adenosine receptor (hA2A) | AA2AR_HUMAN | ADENOSINE A2 | ADENOSINE A2a | ADORA2 | ADORA2A | Adenosine A2A receptor (A2AAR) |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44716.46 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P29274 |
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| Residue: | 412 |
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| Sequence: | MPIMGSSVYITVELAIAVLAILGNVLVCWAVWLNSNLQNVTNYFVVSLAAADIAVGVLAI
PFAITISTGFCAACHGCLFIACFVLVLTQSSIFSLLAIAIDRYIAIRIPLRYNGLVTGTR
AKGIIAICWVLSFAIGLTPMLGWNNCGQPKEGKNHSQGCGEGQVACLFEDVVPMNYMVYF
NFFACVLVPLLLMLGVYLRIFLAARRQLKQMESQPLPGERARSTLQKEVHAAKSLAIIVG
LFALCWLPLHIINCFTFFCPDCSHAPLWLMYLAIVLSHTNSVVNPFIYAYRIREFRQTFR
KIIRSHVLRQQEPFKAAGTSARVLAAHGSDGEQVSLRLNGHPPGVWANGSAPHPERRPNG
YALGLVSGGSAQESQGNTGLPDVELLSHELKGVCPEPPGLDDPLAQDGAGVS
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| BDBM633503 |
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| n/a |
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| Name | BDBM633503 |
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| Synonyms: | 6-[6-amino-1-[(4-amino-2,6-difluoro-phenyl)methyl]pyrazolo[3,4-d]pyrimidine-4-yl]pyridine-2-carbonitrile | US11806350, Compound 223 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H12F2N8 |
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| Mol. Mass. | 378.3383 |
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| SMILES | Nc1cc(F)c(Cn2ncc3c(nc(N)nc23)-c2cccc(n2)C#N)c(F)c1 |
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| Structure | 
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