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TargetAdenosine receptor A1
LigandBDBM633515
Substrate/Competitorn/a
Meas. Tech.Human Adenosine A2A Receptor Binding Assay
Ki 110±n/a nM
Citation Kim, KKim, JMoon, ASong, DLee, YJung, J Prevention and/or treatment of CNS disorders US Patent US11806350 Publication Date 11/7/2023
More Info.:Get all data from this article,  Assay Method
 
Adenosine receptor A1
Name:Adenosine receptor A1
Synonyms:A1 adenosine receptor (hA1) | A1AR | AA1R_HUMAN | ADENOSINE A1 | ADORA1 | Adenosine A1 receptor (A1AR) | Adenosine A1-receptor | Adenosine receptor A1 (A1) | Adenosine receptor A1 (hA1) | Adenosine transporter (AdT)
Type:G Protein-Coupled Receptor (GPCR)
Mol. Mass.:36520.92
Organism:Homo sapiens (Human)
Description:P30542
Residue:326
Sequence:
MPPSISAFQAAYIGIEVLIALVSVPGNVLVIWAVKVNQALRDATFCFIVSLAVADVAVGA
LVIPLAILINIGPQTYFHTCLMVACPVLILTQSSILALLAIAVDRYLRVKIPLRYKMVVT
PRRAAVAIAGCWILSFVVGLTPMFGWNNLSAVERAWAANGSMGEPVIKCEFEKVISMEYM
VYFNFFVWVLPPLLLMVLIYLEVFYLIRKQLNKKVSASSGDPQKYYGKELKIAKSLALIL
FLFALSWLPLHILNCITLFCPSCHKPSILTYIAIFLTHGNSAMNPIVYAFRIQKFRVTFL
KIWNDHFRCQPAPPIDEDLPEERPDD
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  Blast E-value cutoff:
BDBM633515
n/a
NameBDBM633515
Synonyms:2-[6-amino-1-[[4-amino-3-(trifluoromethyl)phenyl]methyl]pyrazolo[3,4-d]pyrimidine-4-yl]pyridine-4-carbonitrile | US11806350, Compound 235
TypeSmall organic molecule
Emp. Form.C19H13F3N8
Mol. Mass.410.3553
SMILESNc1nc(-c2cc(ccn2)C#N)c2cnn(Cc3ccc(N)c(c3)C(F)(F)F)c2n1
Structure
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