| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Egl nine homolog 1 [179-426] |
|---|
| Ligand | BDBM102348 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Activity Assay |
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| pH | 7.5±n/a |
|---|
| Temperature | 298.15±n/a K |
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| IC50 | 14000±n/a nM |
|---|
| Comments | extracted |
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| Citation |  Shalwitz, R; Gardner, JH Methods for increasing the stabilization of hypoxia inducible factor-α US Patent US9278930 Publication Date 3/8/2016 |
|---|
| More Info.: | Get all data from this article, Assay Method |
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| |
| Egl nine homolog 1 [179-426] |
|---|
| Name: | Egl nine homolog 1 [179-426] |
|---|
| Synonyms: | C1orf12 | EGLN1 | EGLN1_HUMAN | Hypoxia-inducible factor prolyl hydroxylase 2 (HIFPH2) |
|---|
| Type: | n/a |
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| Mol. Mass.: | 27759.84 |
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| Organism: | Homo sapiens (Human) |
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| Description: | EGLN-1-179/426 |
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| Residue: | 248 |
|---|
| Sequence: | LRPNGQTKPLPALKLALEYIVPCMNKHGICVVDDFLGKETGQQIGDEVRALHDTGKFTDG
QLVSQKSDSSKDIRGDKITWIEGKEPGCETIGLLMSSMDDLIRHCNGKLGSYKINGRTKA
MVACYPGNGTGYVRHVDNPNGDGRCVTCIYYLNKDWDAKVSGGILRIFPEGKAQFADIEP
KFDRLLFFWSDRRNPHEVQPAYATRYAITVWYFDADERARAKVKYLTGEKGVRVELNKPS
DSVGKDVF
|
|
|
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| BDBM102348 |
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| n/a |
|---|
| Name | BDBM102348 |
|---|
| Synonyms: | US10562854, No. A41 | US8536181, A41 | US9278930, A41 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C22H28ClN3O4 |
|---|
| Mol. Mass. | 433.928 |
|---|
| SMILES | CC(C)(C)OC(=O)N1CCN(Cc2ccn(Cc3ccc(Cl)cc3)c(=O)c2O)CC1 |
|---|
| Structure | 
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