| Reaction Details |
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 | Report a problem with these data |
| Target | N-acylethanolamine-hydrolyzing acid amidase |
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| Ligand | BDBM233783 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | UPLC/MS Assay |
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| pH | 4.5±n/a |
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| Temperature | 310.15±n/a K |
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| IC50 | 14±n/a nM |
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| Comments | extracted |
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| Citation |  Piomelli, D; Bandiera, T; Mor, M; Tarzia, G; Bertozzi, F; Ponzano, S Disubstituted beta-lactones as inhibitors of N-acylethanolamine acid amidase (NAAA) US Patent US9353075 Publication Date 5/31/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| N-acylethanolamine-hydrolyzing acid amidase |
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| Name: | N-acylethanolamine-hydrolyzing acid amidase |
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| Synonyms: | ASAH-like protein | ASAHL | Acid ceramidase-like protein | N-acylethanolamine-hydrolyzing acid amidase | N-acylsphingosine amidohydrolase-like | N-acylsphingosine-amidohydrolase | NAAA | NAAA_HUMAN | PLT |
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| Type: | Enzyme |
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| Mol. Mass.: | 40073.12 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q02083 |
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| Residue: | 359 |
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| Sequence: | MRTADREARPGLPSLLLLLLAGAGLSAASPPAAPRFNVSLDSVPELRWLPVLRHYDLDLV
RAAMAQVIGDRVPKWVHVLIGKVVLELERFLPQPFTGEIRGMCDFMNLSLADCLLVNLAY
ESSVFCTSIVAQDSRGHIYHGRNLDYPFGNVLRKLTVDVQFLKNGQIAFTGTTFIGYVGL
WTGQSPHKFTVSGDERDKGWWWENAIAALFRRHIPVSWLIRATLSESENFEAAVGKLAKT
PLIADVYYIVGGTSPREGVVITRNRDGPADIWPLDPLNGAWFRVETNYDHWKPAPKEDDR
RTSAIKALNATGQANLSLEALFQILSVVPVYNNFTIYTTVMSAGSPDKYMTRIRNPSRK
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| BDBM233783 |
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| n/a |
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| Name | BDBM233783 |
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| Synonyms: | US9353075, 22 |
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| Type | Small organic molecule |
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| Emp. Form. | C17H23NO4 |
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| Mol. Mass. | 305.3688 |
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| SMILES | CC(CCCCc1ccccc1)OC(=O)N[C@@H]1[C@H](C)OC1=O |r,w:1.0| |
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| Structure | 
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