Reaction Details | |||
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Target | Amine oxidase [flavin-containing] B | ||
Ligand | BDBM254546 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Fluorescence-Based (Inhibitor)-Screening Assay | ||
pH | 7.5±n/a | ||
Temperature | 310.15±n/a K | ||
Ki | >40000±n/a nM | ||
Comments | extracted | ||
Citation | Ortega Muñoz, A; Fyfe, MC; Martinell Pedemonte, M; Estiarte Martínez, M; Valls Vidal, N; Kurz, G; Castro Palomino Laria, JC (Hetero)aryl cyclopropylamine compounds as LSD1 inhibitors US Patent US9469597 Publication Date 10/18/2016 | ||
More Info.: | Get all data from this article, Assay Method | ||
Amine oxidase [flavin-containing] B | |||
Name: | Amine oxidase [flavin-containing] B | ||
Synonyms: | AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB) | ||
Type: | Protein | ||
Mol. Mass.: | 58768.76 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P27338 | ||
Residue: | 520 | ||
Sequence: |
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BDBM254546 | |||
n/a | |||
Name | BDBM254546 | ||
Synonyms: | US10214477, Example 3 | US9469597, 1 | US9670136, 5 (trans)-N1-((1R,2S)-2-phenylcyclopropyl)cyclohexane-1,4-diamine | ||
Type | Small organic molecule | ||
Emp. Form. | C15H22N2 | ||
Mol. Mass. | 230.3486 | ||
SMILES | NC1CCC(CC1)N[C@H]1C[C@@H]1c1ccccc1 |r,wU:10.12,wD:8.8,(6.06,2.69,;4.73,1.93,;4.73,.38,;3.4,-.38,;2.06,.38,;2.06,1.93,;3.4,2.69,;.73,-.38,;-.6,.38,;-1.37,1.72,;-2.14,.38,;-3.48,-.38,;-4.81,.38,;-6.14,-.38,;-6.14,-1.93,;-4.81,-2.69,;-3.48,-1.93,)| | ||
Structure |