| Reaction Details |
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 | Report a problem with these data |
| Target | Bromodomain-containing protein 4 [368-440] |
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| Ligand | BDBM259896 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| IC50 | 1256±n/a nM |
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| Citation |  Durden, DL; Morales, GA; Garlich, JR Thienopyranones as kinase and epigenetic inhibitors US Patent US9505780 Publication Date 11/29/2016 |
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| More Info.: | Get all data from this article, Assay Method |
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| Bromodomain-containing protein 4 [368-440] |
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| Name: | Bromodomain-containing protein 4 [368-440] |
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| Synonyms: | BRD4 | BRD4_HUMAN | Bromo domain 2 | Bromodomain-containing protein 4 (BD2) | Bromodomain-containing protein 4 (BRD4) Bromo 2 | Bromodomain-containing protein 4 (BRD4)(BD2) | Bromodomain-containing protein 4 (BRD4)(Bromo 2) | Bromodomain-containing protein 4 Bromo 2 domain(BRD4 BD2) | Bromodomain-containing protein 4 Bromodomain 2 (BRD4-2) | Bromodomain-containing protein 4 Domain 2 | HUNK1 |
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| Type: | Protein |
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| Mol. Mass.: | 8564.63 |
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| Organism: | Homo sapiens (Human) |
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| Description: | BD2 (368-440 aa) of O60885 |
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| Residue: | 73 |
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| Sequence: | KHAAYAWPFYKPVDVEALGLHDYCDIIKHPMDMSTIKSKLEAREYRDAQEFGADVRLMFS
NCYKYNPPDHEVV
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| BDBM259896 |
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| n/a |
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| Name | BDBM259896 |
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| Synonyms: | US10308662, Compound 137 | US9505780, 137 |
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| Type | Small organic molecule |
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| Emp. Form. | C26H25N3O4S |
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| Mol. Mass. | 475.559 |
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| SMILES | Cc1ccc(C)c(NC(=O)Nc2cccc(c2)-c2csc3c2oc(cc3=O)N2CCOCC2)c1 |
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| Structure | 
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