Reaction Details | |||
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Target | Non-receptor tyrosine-protein kinase TYK2 [888-1187] | ||
Ligand | BDBM410177 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Caliper mobility shift assay | ||
IC50 | 1100±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Non-receptor tyrosine-protein kinase TYK2 [888-1187] | |||
Name: | Non-receptor tyrosine-protein kinase TYK2 [888-1187] | ||
Synonyms: | Non-receptor tyrosine-protein kinase TYK2 (aa 888-1187) | TYK2 | TYK2 (aa 888-1187) | TYK2_HUMAN | ||
Type: | Protein | ||
Mol. Mass.: | 34527.73 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P29597[888-1187] | ||
Residue: | 300 | ||
Sequence: |
| ||
BDBM410177 | |||
n/a | |||
Name | BDBM410177 | ||
Synonyms: | US10370375, Example 25 | ||
Type | Small organic molecule | ||
Emp. Form. | C15H20N4O5S | ||
Mol. Mass. | 368.408 | ||
SMILES | CNS(=O)(=O)C[C@H]1CCC(CC1)Oc1c(cnc2[nH]ccc12)[N+]([O-])=O |r,wU:6.5,(4.29,4.1,;4.29,5.64,;2.96,6.41,;1.63,7.18,;4.29,7.18,;2.96,4.87,;1.63,4.1,;1.63,2.56,;.29,1.79,;-1.04,2.56,;-1.04,4.1,;.29,4.87,;-2.38,1.79,;-2.38,.25,;-3.71,-.52,;-3.71,-2.06,;-2.38,-2.83,;-1.04,-2.06,;.42,-2.54,;1.33,-1.29,;.42,-.05,;-1.04,-.52,;-5.04,.25,;-5.04,1.79,;-6.38,-.52,)| | ||
Structure | ![]() |