| Reaction Details |
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 | Report a problem with these data |
| Target | Epoxide hydrolase |
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| Ligand | BDBM25730 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Inhibition Assay |
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| IC50 | 56.0±n/a nM |
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| Citation |  Guedes, AG; Hammock, BD; Morisseau, C Treatment of inflammatory disorders in non-human mammals US Patent US10383835 Publication Date 8/20/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Epoxide hydrolase |
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| Name: | Epoxide hydrolase |
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| Synonyms: | EPHX1 |
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| Type: | Enzyme |
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| Mol. Mass.: | 52112.47 |
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| Organism: | Ovis aries (Sheep) |
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| Description: | W5Q7Q6 |
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| Residue: | 451 |
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| Sequence: | MWLEILLASVLGFVIYWFVSKDKEETLPLEDGWWGPGVRPTAGEDKSIRPFKVETSDEEI
NDLHQRIDRVRLTPPLEDSRFHYGFNSNYLKKIISYWRNEFDWRKQVEILNKYPHFKTKI
EGLDIHFIHVKPPNLPSGQTPKPLLMVHGWPGSFYEFYKIIPLLTDPKNHGLSDEHVFEV
ICPSIPGYGFSEASSKKGFNSVATARIFYKLMLRLGFQKFYIQGGDWGALICTNMAQLVP
SHIKGLHLNMALILRNFYTLTLPLGRCFGGLFGYTERDMELIYPFKKIFFSLLRESGYMH
IQSTKPDTVGCALNDSPVGLAAYILEKFSTWTNSEFRDLEDGGLERKFSLDDLLTGIMLY
WTTGTITSSQRFYKENLAQVNKHETLKVYVPTGFAAFPCELIHSPEKWVKTKYPKLISYS
YMPRGGHFAAFEEPELLAQDIRKFVGLQERQ
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| BDBM25730 |
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| n/a |
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| Name | BDBM25730 |
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| Synonyms: | 3-(4-chlorophenyl)-1-(3,4-dichlorophenyl)urea | US10383835, Compound 295 | US8815951, 3-(4-chlorophenyl)-1-(3,4-dichlorophenyl)urea | Urea-based compound, 11 | cid_7547 |
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| Type | Small organic molecule |
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| Emp. Form. | C13H9Cl3N2O |
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| Mol. Mass. | 315.582 |
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| SMILES | Clc1ccc(NC(=O)Nc2ccc(Cl)c(Cl)c2)cc1 |
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| Structure | 
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