| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Bombesin receptor subtype-3 |
|---|
| Ligand | BDBM428851 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | BB2 Receptor Antagonistic Activity |
|---|
| IC50 | 3.00±n/a nM |
|---|
| Citation |  Hisamichi, H; Shimada, I; Ishihara, T; Takuwa, T; Shimizu, T; Ishikawa, N; Maeno, K; Seki, N Tetrahydroisoquinolin-1-one derivative or salt thereof US Patent US10532048 Publication Date 1/14/2020 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Bombesin receptor subtype-3 |
|---|
| Name: | Bombesin receptor subtype-3 |
|---|
| Synonyms: | BRS-3 | BRS3 | BRS3_HUMAN | Bombesin 3 | Bombesin like receptor 3 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 44424.45 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Bombesin 3 BRS3 HUMAN::P32247 |
|---|
| Residue: | 399 |
|---|
| Sequence: | MAQRQPHSPNQTLISITNDTESSSSVVSNDNTNKGWSGDNSPGIEALCAIYITYAVIISV
GILGNAILIKVFFKTKSMQTVPNIFITSLAFGDLLLLLTCVPVDATHYLAEGWLFGRIGC
KVLSFIRLTSVGVSVFTLTILSADRYKAVVKPLERQPSNAILKTCVKAGCVWIVSMIFAL
PEAIFSNVYTFRDPNKNMTFESCTSYPVSKKLLQEIHSLLCFLVFYIIPLSIISVYYSLI
ARTLYKSTLNIPTEEQSHARKQIESRKRIARTVLVLVALFALCWLPNHLLYLYHSFTSQT
YVDPSAMHFIFTIFSRVLAFSNSCVNPFALYWLSKSFQKHFKAQLFCCKAERPEPPVADT
SLTTLAVMGTVPGTGSIQMSEISVTSFTGCSVKQAEDRF
|
|
|
|---|
| BDBM428851 |
|---|
| n/a |
|---|
| Name | BDBM428851 |
|---|
| Synonyms: | US10532048, Example 236 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C31H33Cl2N3O4S |
|---|
| Mol. Mass. | 614.582 |
|---|
| SMILES | C[C@@H](NC(=O)[C@H]1[C@@H](N([C@H]2CCCC[C@@H]2NS(C)(=O)=O)C(=O)c2ccccc12)c1ccc(Cl)cc1Cl)c1ccccc1 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
