| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Bombesin receptor subtype-3 |
|---|
| Ligand | BDBM428857 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | BB2 Receptor Antagonistic Activity |
|---|
| IC50 | 7.40±n/a nM |
|---|
| Citation |  Hisamichi, H; Shimada, I; Ishihara, T; Takuwa, T; Shimizu, T; Ishikawa, N; Maeno, K; Seki, N Tetrahydroisoquinolin-1-one derivative or salt thereof US Patent US10532048 Publication Date 1/14/2020 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Bombesin receptor subtype-3 |
|---|
| Name: | Bombesin receptor subtype-3 |
|---|
| Synonyms: | BRS-3 | BRS3 | BRS3_HUMAN | Bombesin 3 | Bombesin like receptor 3 |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 44424.45 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Bombesin 3 BRS3 HUMAN::P32247 |
|---|
| Residue: | 399 |
|---|
| Sequence: | MAQRQPHSPNQTLISITNDTESSSSVVSNDNTNKGWSGDNSPGIEALCAIYITYAVIISV
GILGNAILIKVFFKTKSMQTVPNIFITSLAFGDLLLLLTCVPVDATHYLAEGWLFGRIGC
KVLSFIRLTSVGVSVFTLTILSADRYKAVVKPLERQPSNAILKTCVKAGCVWIVSMIFAL
PEAIFSNVYTFRDPNKNMTFESCTSYPVSKKLLQEIHSLLCFLVFYIIPLSIISVYYSLI
ARTLYKSTLNIPTEEQSHARKQIESRKRIARTVLVLVALFALCWLPNHLLYLYHSFTSQT
YVDPSAMHFIFTIFSRVLAFSNSCVNPFALYWLSKSFQKHFKAQLFCCKAERPEPPVADT
SLTTLAVMGTVPGTGSIQMSEISVTSFTGCSVKQAEDRF
|
|
|
|---|
| BDBM428857 |
|---|
| n/a |
|---|
| Name | BDBM428857 |
|---|
| Synonyms: | US10532048, Example 701 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C33H35Cl2N3O6S |
|---|
| Mol. Mass. | 672.619 |
|---|
| SMILES | CS(=O)(=O)N[C@H]1CCCC[C@@H]1N1[C@H]([C@H](C(=O)NCCc2ccc(CC(O)=O)cc2)c2ccccc2C1=O)c1ccc(Cl)cc1Cl |r| |
|---|
| Structure | 
|
|---|
Search and Browse
