| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Adenosine receptor A3 |
|---|
| Ligand | BDBM434835 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Binding Assays |
|---|
| Ki | 0.850±0.10 nM |
|---|
| Citation |  Jacobson, KA; Tosh, DK; Salvemini, D A3 adenosine receptor agonists US Patent US10577368 Publication Date 3/3/2020 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Adenosine receptor A3 |
|---|
| Name: | Adenosine receptor A3 |
|---|
| Synonyms: | A3 adenosine receptor (hA3) | AA3R_HUMAN | ADORA3 | Adenosine A3 receptor (A3AR) |
|---|
| Type: | G Protein-Coupled Receptor (GPCR) |
|---|
| Mol. Mass.: | 36197.32 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P0DMS8 |
|---|
| Residue: | 318 |
|---|
| Sequence: | MPNNSTALSLANVTYITMEIFIGLCAIVGNVLVICVVKLNPSLQTTTFYFIVSLALADIA
VGVLVMPLAIVVSLGITIHFYSCLFMTCLLLIFTHASIMSLLAIAVDRYLRVKLTVRYKR
VTTHRRIWLALGLCWLVSFLVGLTPMFGWNMKLTSEYHRNVTFLSCQFVSVMRMDYMVYF
SFLTWIFIPLVVMCAIYLDIFYIIRNKLSLNLSNSKETGAFYGREFKTAKSLFLVLFLFA
LSWLPLSIINCIIYFNGEVPQLVLYMGILLSHANSMMNPIVYAYKIKKFKETYLLILKAC
VVCHPSDSLDTSIEKNSE
|
|
|
|---|
| BDBM434835 |
|---|
| n/a |
|---|
| Name | BDBM434835 |
|---|
| Synonyms: | US10577368, Compound 117 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H23N9O3 |
|---|
| Mol. Mass. | 449.4658 |
|---|
| SMILES | CNC(=O)[C@]12CC1[C@H]([C@H](O)C2O)n1cnc2c(NCCc3ccccc3)nc(N=[N+]=[N-])nc12 |r| |
|---|
| Structure | 
|
|---|
Search and Browse
