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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Lysine-specific histone demethylase 1A | ||
| Ligand | BDBM439014 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | FL-LSD1 LC-MS Assay | ||
| IC50 | 2.00±n/a nM | ||
| Citation |  Du-Cuny, L; Xiao, Q; Xun, G; Zheng, Q Substituted 5-cyanoindole compounds and uses thereof US Patent US10604502 Publication Date 3/31/2020 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Lysine-specific histone demethylase 1A | |||
| Name: | Lysine-specific histone demethylase 1A | ||
| Synonyms: | AOF2 | BRAF35-HDAC complex protein BHC110 | Flavin-containing amine oxidase domain-containing protein 2 | KDM1 | KDM1A | KDM1A_HUMAN | KIAA0601 | LSD1 | Lysine-specific demethylase 1 (LSD1) | Lysine-specific histone demethylase 1 | Lysine-specific histone demethylase 1 (LSD1) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 92901.01 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O60341 | ||
| Residue: | 852 | ||
| Sequence: |
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| BDBM439014 | |||
| n/a | |||
| Name | BDBM439014 | ||
| Synonyms: | US10604502, Ex # 2 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C21H21ClN4O | ||
| Mol. Mass. | 380.871 | ||
| SMILES | Cc1cc2n(cc(-c3cncc(N)c3Cl)c2cc1C#N)[C@@H]1CC[C@H](O)CC1 |r,wU:20.22,23.26,(-4.05,-.81,;-2.71,-.04,;-1.38,-.81,;-.05,-.04,;1.42,-.51,;2.32,.73,;1.42,1.98,;1.89,3.44,;.86,4.59,;1.34,6.05,;2.85,6.37,;3.88,5.23,;5.38,5.55,;3.4,3.76,;4.43,2.62,;-.05,1.5,;-1.38,2.27,;-2.71,1.5,;-4.05,2.27,;-5.38,3.04,;1.89,-1.98,;.86,-3.12,;1.34,-4.59,;2.85,-4.91,;3.32,-6.37,;3.88,-3.76,;3.4,-2.3,)| | ||
| Structure | 
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