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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Lysine-specific histone demethylase 1A | ||
| Ligand | BDBM439015 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | FL-LSD1 LC-MS Assay | ||
| IC50 | 5.00±n/a nM | ||
| Citation |  Du-Cuny, L; Xiao, Q; Xun, G; Zheng, Q Substituted 5-cyanoindole compounds and uses thereof US Patent US10604502 Publication Date 3/31/2020 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Lysine-specific histone demethylase 1A | |||
| Name: | Lysine-specific histone demethylase 1A | ||
| Synonyms: | AOF2 | BRAF35-HDAC complex protein BHC110 | Flavin-containing amine oxidase domain-containing protein 2 | KDM1 | KDM1A | KDM1A_HUMAN | KIAA0601 | LSD1 | Lysine-specific demethylase 1 (LSD1) | Lysine-specific histone demethylase 1 | Lysine-specific histone demethylase 1 (LSD1) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 92901.01 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O60341 | ||
| Residue: | 852 | ||
| Sequence: |
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| BDBM439015 | |||
| n/a | |||
| Name | BDBM439015 | ||
| Synonyms: | US10604502, Ex # 3 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H22F2N4O | ||
| Mol. Mass. | 396.4331 | ||
| SMILES | Cc1cc2n(cc(-c3cncc(N)c3C(F)F)c2cc1C#N)[C@H]1CC[C@H](O)CC1 |r,wU:22.24,wD:25.28,(-4.33,-.81,;-2.99,-.04,;-1.66,-.81,;-.32,-.04,;1.14,-.51,;2.05,.73,;1.14,1.98,;1.62,3.44,;.59,4.59,;1.06,6.05,;2.57,6.37,;3.6,5.23,;5.1,5.55,;3.12,3.76,;4.15,2.62,;5.66,2.94,;3.68,1.15,;-.32,1.5,;-1.66,2.27,;-2.99,1.5,;-4.33,2.27,;-5.66,3.04,;1.62,-1.98,;3.12,-2.3,;3.6,-3.76,;2.57,-4.91,;3.04,-6.37,;1.06,-4.59,;.59,-3.12,)| | ||
| Structure | 
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