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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Lysine-specific histone demethylase 1A | ||
| Ligand | BDBM439100 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | FL-LSD1 LC-MS Assay | ||
| IC50 | 1.000±n/a nM | ||
| Citation |  Du-Cuny, L; Xiao, Q; Xun, G; Zheng, Q Substituted 5-cyanoindole compounds and uses thereof US Patent US10604502 Publication Date 3/31/2020 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Lysine-specific histone demethylase 1A | |||
| Name: | Lysine-specific histone demethylase 1A | ||
| Synonyms: | AOF2 | BRAF35-HDAC complex protein BHC110 | Flavin-containing amine oxidase domain-containing protein 2 | KDM1 | KDM1A | KDM1A_HUMAN | KIAA0601 | LSD1 | Lysine-specific demethylase 1 (LSD1) | Lysine-specific histone demethylase 1 | Lysine-specific histone demethylase 1 (LSD1) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 92901.01 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O60341 | ||
| Residue: | 852 | ||
| Sequence: |
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| BDBM439100 | |||
| n/a | |||
| Name | BDBM439100 | ||
| Synonyms: | US10604502, Ex # 88 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C26H28N4O | ||
| Mol. Mass. | 412.5267 | ||
| SMILES | Cc1cc2n(cc(-c3cncc4NC(C)(C)C=Cc34)c2cc1C#N)[C@H]1CC[C@H](O)CC1 |r,wU:24.27,wD:27.31,c:16,(-6.1,.69,;-4.64,1.16,;-3.49,.13,;-2.03,.61,;-.69,-.16,;.45,.87,;-.17,2.28,;.6,3.61,;-.17,4.94,;.6,6.28,;2.14,6.28,;2.91,4.94,;4.45,4.94,;5.22,3.61,;6.55,4.38,;6.55,2.84,;4.45,2.28,;2.91,2.28,;2.14,3.61,;-1.71,2.12,;-2.85,3.15,;-4.32,2.67,;-5.46,3.7,;-6.55,4.79,;-.53,-1.69,;.88,-2.3,;1.07,-3.82,;-.16,-4.75,;.02,-6.28,;-1.58,-4.14,;-1.76,-2.62,)| | ||
| Structure | 
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