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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Lysine-specific histone demethylase 1A | ||
| Ligand | BDBM439107 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | FL-LSD1 LC-MS Assay | ||
| IC50 | 5.00±n/a nM | ||
| Citation |  Du-Cuny, L; Xiao, Q; Xun, G; Zheng, Q Substituted 5-cyanoindole compounds and uses thereof US Patent US10604502 Publication Date 3/31/2020 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Lysine-specific histone demethylase 1A | |||
| Name: | Lysine-specific histone demethylase 1A | ||
| Synonyms: | AOF2 | BRAF35-HDAC complex protein BHC110 | Flavin-containing amine oxidase domain-containing protein 2 | KDM1 | KDM1A | KDM1A_HUMAN | KIAA0601 | LSD1 | Lysine-specific demethylase 1 (LSD1) | Lysine-specific histone demethylase 1 | Lysine-specific histone demethylase 1 (LSD1) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 92901.01 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O60341 | ||
| Residue: | 852 | ||
| Sequence: |
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| BDBM439107 | |||
| n/a | |||
| Name | BDBM439107 | ||
| Synonyms: | US10604502, Ex # 95 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C27H29N3O | ||
| Mol. Mass. | 411.5387 | ||
| SMILES | Cc1cc2n(cc(-c3cccc4NC(C)(C)C=Cc34)c2cc1C#N)[C@H]1CC[C@H](O)CC1 |r,wU:24.27,wD:27.31,c:16,(-5.32,-.81,;-3.98,-.04,;-2.65,-.81,;-1.32,-.04,;.15,-.51,;1.05,.73,;.15,1.98,;.62,3.44,;-.41,4.59,;.07,6.05,;1.58,6.37,;2.61,5.23,;4.11,5.55,;5.14,4.4,;6.65,4.72,;5.54,5.89,;4.67,2.94,;3.16,2.62,;2.13,3.76,;-1.32,1.5,;-2.65,2.27,;-3.98,1.5,;-5.32,2.27,;-6.65,3.04,;.62,-1.98,;2.13,-2.3,;2.61,-3.76,;1.58,-4.91,;2.05,-6.37,;.07,-4.59,;-.41,-3.12,)| | ||
| Structure | 
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