Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Lysine-specific histone demethylase 1A | ||
| Ligand | BDBM439120 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | FL-LSD1 LC-MS Assay | ||
| IC50 | 1.000±n/a nM | ||
| Citation |  Du-Cuny, L; Xiao, Q; Xun, G; Zheng, Q Substituted 5-cyanoindole compounds and uses thereof US Patent US10604502 Publication Date 3/31/2020 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Lysine-specific histone demethylase 1A | |||
| Name: | Lysine-specific histone demethylase 1A | ||
| Synonyms: | AOF2 | BRAF35-HDAC complex protein BHC110 | Flavin-containing amine oxidase domain-containing protein 2 | KDM1 | KDM1A | KDM1A_HUMAN | KIAA0601 | LSD1 | Lysine-specific demethylase 1 (LSD1) | Lysine-specific histone demethylase 1 | Lysine-specific histone demethylase 1 (LSD1) | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 92901.01 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O60341 | ||
| Residue: | 852 | ||
| Sequence: |
| ||
| BDBM439120 | |||
| n/a | |||
| Name | BDBM439120 | ||
| Synonyms: | US10604502, Ex # 108 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C23H26ClN5O2S | ||
| Mol. Mass. | 472.003 | ||
| SMILES | CN(C)S(=O)(=O)[C@H]1CC[C@@H](CC1)n1cc(-c2cncc(N)c2Cl)c2cc(C#N)c(C)cc12 |r,wU:9.12,wD:6.5,(5.64,-4.74,;4.55,-5.83,;4.95,-7.32,;3.06,-5.43,;1.58,-5.03,;1.97,-6.52,;2.59,-3.96,;3.62,-2.82,;3.14,-1.36,;1.64,-1.04,;.61,-2.18,;1.08,-3.64,;1.16,.43,;2.06,1.68,;1.16,2.92,;1.64,4.39,;.61,5.53,;1.08,6.99,;2.59,7.32,;3.62,6.17,;5.12,6.49,;3.14,4.71,;4.17,3.56,;-.31,2.45,;-1.64,3.22,;-2.97,2.45,;-4.31,3.22,;-5.64,3.99,;-2.97,.91,;-4.31,.14,;-1.64,.14,;-.31,.91,)| | ||
| Structure | 
| ||