| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Retinaldehyde-binding protein 1 |
|---|
| Ligand | BDBM323478 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | In Vitro Isomerase Inhibition Assay |
|---|
| IC50 | 55.0±n/a nM |
|---|
| Citation |  Scott, IL; Kuksa, VA; Orme, MW; Little, Jr., TL; Gall, A; Hong, F Alkoxy compounds for disease treatment US Patent US10639286 Publication Date 5/5/2020 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Retinaldehyde-binding protein 1 |
|---|
| Name: | Retinaldehyde-binding protein 1 |
|---|
| Synonyms: | CRALBP | Cellular retinaldehyde-binding protein | RLBP1 | RLBP1_HUMAN |
|---|
| Type: | Enzyme Catalytic Domain |
|---|
| Mol. Mass.: | 36462.25 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P12271 |
|---|
| Residue: | 317 |
|---|
| Sequence: | MSEGVGTFRMVPEEEQELRAQLEQLTTKDHGPVFGPCSQLPRHTLQKAKDELNEREETRE
EAVRELQEMVQAQAASGEELAVAVAERVQEKDSGFFLRFIRARKFNVGRAYELLRGYVNF
RLQYPELFDSLSPEAVRCTIEAGYPGVLSSRDKYGRVVMLFNIENWQSQEITFDEILQAY
CFILEKLLENEETQINGFCIIENFKGFTMQQAASLRTSDLRKMVDMLQDSFPARFKAIHF
IHQPWYFTTTYNVVKPFLKSKLLERVFVHGDDLSGFYQEIDENILPSDFGGTLPKYDGKA
VAEQLFGPQAQAENTAF
|
|
|
|---|
| BDBM323478 |
|---|
| n/a |
|---|
| Name | BDBM323478 |
|---|
| Synonyms: | 3-Amino-1-(3-(5-(Benzyloxy)Pentyloxy)Phenyl)Propan-1-Ol | US10188615, Example 115 | US10639286, Example 115 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C21H29NO3 |
|---|
| Mol. Mass. | 343.4599 |
|---|
| SMILES | NCCC(O)c1cccc(OCCCCCOCc2ccccc2)c1 |
|---|
| Structure | 
|
|---|
Search and Browse
