| Reaction Details |
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 | Report a problem with these data |
| Target | Ubiquitin carboxyl-terminal hydrolase 30 |
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| Ligand | BDBM441759 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Biochemical Assay |
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| IC50 | <100±n/a nM |
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| Citation |  Gibson, KR; Jones, A; Kemp, MI; Madin, A; Stockley, ML; Whitlock, GA; Woodrow, MD Compounds US Patent US10640498 Publication Date 5/5/2020 |
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| More Info.: | Get all data from this article, Assay Method |
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| Ubiquitin carboxyl-terminal hydrolase 30 |
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| Name: | Ubiquitin carboxyl-terminal hydrolase 30 |
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| Synonyms: | Deubiquitinating enzyme 30 | UBP30_HUMAN | USP30 | Ub-specific protease 30 | Ubiquitin carboxyl-terminal hydrolase 30 (USP30) | Ubiquitin thioesterase 30 | Ubiquitin-specific-processing protease 30 |
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| Type: | Protein |
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| Mol. Mass.: | 58522.90 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q70CQ3 |
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| Residue: | 517 |
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| Sequence: | MLSSRAEAAMTAADRAIQRFLRTGAAVRYKVMKNWGVIGGIAAALAAGIYVIWGPITERK
KRRKGLVPGLVNLGNTCFMNSLLQGLSACPAFIRWLEEFTSQYSRDQKEPPSHQYLSLTL
LHLLKALSCQEVTDDEVLDASCLLDVLRMYRWQISSFEEQDAHELFHVITSSLEDERDRQ
PRVTHLFDVHSLEQQSEITPKQITCRTRGSPHPTSNHWKSQHPFHGRLTSNMVCKHCEHQ
SPVRFDTFDSLSLSIPAATWGHPLTLDHCLHHFISSESVRDVVCDNCTKIEAKGTLNGEK
VEHQRTTFVKQLKLGKLPQCLCIHLQRLSWSSHGTPLKRHEHVQFNEFLMMDIYKYHLLG
HKPSQHNPKLNKNPGPTLELQDGPGAPTPVLNQPGAPKTQIFMNGACSPSLLPTLSAPMP
FPLPVVPDYSSSTYLFRLMAVVVHHGDMHSGHFVTYRRSPPSARNPLSTSNQWLWVSDDT
VRKASLQEVLSSSAYLLFYERVLSRMQHQSQECKSEE
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| BDBM441759 |
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| n/a |
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| Name | BDBM441759 |
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| Synonyms: | (R)-3-(5-(3-Chlorophenyl)-2,3-dihydro-1H-pyrrolo[2,3-b]pyridine-1-carbonyl)-3-fluoropyrrolidine-1-carbonitrile | US10640498, Example 56 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H16ClFN4O |
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| Mol. Mass. | 370.808 |
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| SMILES | F[C@@]1(CCN(C1)C#N)C(=O)N1CCc2cc(cnc12)-c1cccc(Cl)c1 |
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| Structure | 
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