| Reaction Details |
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 | Report a problem with these data |
| Target | Mu-type opioid receptor |
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| Ligand | BDBM50531913 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | OPR Mu Antagonist Assay |
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| IC50 | >1000±n/a nM |
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| Citation |  Roberts, E; Guerrero, MA; Urbano, M; Rosen, H; Jones, RM; Laxamana, CM; Zhao, X; Turtle, ED Kappa opioid receptor antagonists and products and methods related thereto US Patent US10676469 Publication Date 6/9/2020 |
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| More Info.: | Get all data from this article, Assay Method |
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| Mu-type opioid receptor |
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| Name: | Mu-type opioid receptor |
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| Synonyms: | M-OR-1 | MOP | MOR-1 | MOR1 | MUOR1 | Mu Opioid Receptor | Mu opiate receptor | OPIATE Mu | OPRM1 | OPRM_HUMAN | hMOP | mu-type opioid receptor isoform MOR-1 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 44789.51 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P35372 |
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| Residue: | 400 |
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| Sequence: | MDSSAAPTNASNCTDALAYSSCSPAPSPGSWVNLSHLDGNLSDPCGPNRTDLGGRDSLCP
PTGSPSMITAITIMALYSIVCVVGLFGNFLVMYVIVRYTKMKTATNIYIFNLALADALAT
STLPFQSVNYLMGTWPFGTILCKIVISIDYYNMFTSIFTLCTMSVDRYIAVCHPVKALDF
RTPRNAKIINVCNWILSSAIGLPVMFMATTKYRQGSIDCTLTFSHPTWYWENLLKICVFI
FAFIMPVLIITVCYGLMILRLKSVRMLSGSKEKDRNLRRITRMVLVVVAVFIVCWTPIHI
YVIIKALVTIPETTFQTVSWHFCIALGYTNSCLNPVLYAFLDENFKRCFREFCIPTSSNI
EQQNSTRIRQNTRDHPSTANTVDRTNHQLENLEAETAPLP
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| BDBM50531913 |
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| n/a |
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| Name | BDBM50531913 |
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| Synonyms: | CHEMBL4584410 | US10676469, Compound 253 | US11124504, Cpd. No. 250 |
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| Type | Small organic molecule |
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| Emp. Form. | C24H30FN5O2 |
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| Mol. Mass. | 439.5257 |
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| SMILES | CCc1cc(F)c2nc(N3CCC(CC3)NC3CCOCC3)c(cc2c1)-c1nc(C)no1 |
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| Structure | 
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