Reaction Details | |||
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Target | Nociceptin receptor | ||
Ligand | BDBM469398 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Human Nociceptin/Orphanin FQ Peptide (hNOP) Receptor Binding Assay | ||
Ki | 0.900±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Nociceptin receptor | |||
Name: | Nociceptin receptor | ||
Synonyms: | KOR-3 | Kappa-type 3 opioid receptor | Mu-type opioid receptor (Mu) | NOP | Nociceptin Receptor (ORL1 Receptor) | Nociceptin receptor (NOP) | Nociceptin receptor (ORL-1) | Nociceptin receptor (ORL1) | Nociceptin/Orphanin FQ, NOP receptor | OOR | OPIATE ORL-1 | OPRL1 | OPRL1 protein | OPRX_HUMAN | ORL1 | ORL1 receptor | Opioid receptor like-1 | Orphanin FQ receptor | Orphanin FQ receptor (ORL1) | P41146 | ||
Type: | G Protein-Coupled Receptor (GPCR) | ||
Mol. Mass.: | 40702.87 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P41146 | ||
Residue: | 370 | ||
Sequence: |
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BDBM469398 | |||
n/a | |||
Name | BDBM469398 | ||
Synonyms: | US10807988, Example SC_3041 | cis-5-[1-[(1-Cyano-cyclobutyl)-methyl]-8-dimethylamino-2-oxo-8-phenyl-1,3- diazaspiro[4.5]decan-3-yl]-pyrimidine-2-carbonitrile | ||
Type | Small organic molecule | ||
Emp. Form. | C27H31N7O | ||
Mol. Mass. | 469.5813 | ||
SMILES | CN(C)[C@]1(CC[C@]2(CN(C(=O)N2CC2(CCC2)C#N)c2cnc(nc2)C#N)CC1)c1ccccc1 |r,wU:6.11,3.2,(3.2,23.24,;3.97,21.91,;5.51,21.91,;3.2,20.58,;2.43,19.24,;.89,19.24,;.12,20.58,;-.79,21.82,;-2.25,21.35,;-2.25,19.81,;-3.5,18.9,;-.79,19.33,;-.31,17.87,;-1.34,16.72,;-2.88,16.64,;-2.8,15.1,;-1.26,15.18,;.14,16.32,;1.63,15.92,;-3.5,22.25,;-3.34,23.78,;-4.58,24.69,;-5.99,24.06,;-6.15,22.53,;-4.91,21.62,;-7.24,24.97,;-8.33,26.06,;.89,21.91,;2.43,21.91,;3.97,19.24,;3.2,17.91,;3.97,16.57,;5.51,16.57,;6.28,17.91,;5.51,19.24,)| | ||
Structure | ![]() |