| Reaction Details |
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 | Report a problem with these data |
| Target | Transitional endoplasmic reticulum ATPase |
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| Ligand | BDBM478222 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Biomol Green Assay |
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| IC50 | 15.0±n/a nM |
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| Citation |  Huryn, DM; Wipf, P; LaPorte, MG Modulators of P97 AAA ATPase activity US Patent US10894782 Publication Date 1/19/2021 |
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| More Info.: | Get all data from this article, Assay Method |
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| Transitional endoplasmic reticulum ATPase |
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| Name: | Transitional endoplasmic reticulum ATPase |
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| Synonyms: | TERA_HUMAN | Transitional endoplasmic reticulum ATPase | VCP | Valosin containing protein, p97 subunit | Valosin-containing protein |
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| Type: | Enzyme |
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| Mol. Mass.: | 89300.63 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P55072 |
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| Residue: | 806 |
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| Sequence: | MASGADSKGDDLSTAILKQKNRPNRLIVDEAINEDNSVVSLSQPKMDELQLFRGDTVLLK
GKKRREAVCIVLSDDTCSDEKIRMNRVVRNNLRVRLGDVISIQPCPDVKYGKRIHVLPID
DTVEGITGNLFEVYLKPYFLEAYRPIRKGDIFLVRGGMRAVEFKVVETDPSPYCIVAPDT
VIHCEGEPIKREDEEESLNEVGYDDIGGCRKQLAQIKEMVELPLRHPALFKAIGVKPPRG
ILLYGPPGTGKTLIARAVANETGAFFFLINGPEIMSKLAGESESNLRKAFEEAEKNAPAI
IFIDELDAIAPKREKTHGEVERRIVSQLLTLMDGLKQRAHVIVMAATNRPNSIDPALRRF
GRFDREVDIGIPDATGRLEILQIHTKNMKLADDVDLEQVANETHGHVGADLAALCSEAAL
QAIRKKMDLIDLEDETIDAEVMNSLAVTMDDFRWALSQSNPSALRETVVEVPQVTWEDIG
GLEDVKRELQELVQYPVEHPDKFLKFGMTPSKGVLFYGPPGCGKTLLAKAIANECQANFI
SIKGPELLTMWFGESEANVREIFDKARQAAPCVLFFDELDSIAKARGGNIGDGGGAADRV
INQILTEMDGMSTKKNVFIIGATNRPDIIDPAILRPGRLDQLIYIPLPDEKSRVAILKAN
LRKSPVAKDVDLEFLAKMTNGFSGADLTEICQRACKLAIRESIESEIRRERERQTNPSAM
EVEEDDPVPEIRRDHFEEAMRFARRSVSDNDIRKYEMFAQTLQQSRGFGSFRFPSGNQGG
AGPSQGSGGGTGGSVYTEDNDDDLYG
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| BDBM478222 |
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| n/a |
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| Name | BDBM478222 |
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| Synonyms: | US10894782, No 108 | US10894782, No 75 |
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| Type | Small organic molecule |
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| Emp. Form. | C30H35N7O3S |
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| Mol. Mass. | 573.709 |
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| SMILES | CN1CCN(CC1)NC(=O)OCC#Cc1ccc(OCc2nnc(SC3CCCC=C3)n2-c2cccnc2)cc1C |c:30| |
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| Structure | 
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