Reaction Details | |||
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Target | Non-receptor tyrosine-protein kinase TYK2 [580-1182] | ||
Ligand | BDBM505110 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Enzymatic Inhibition Assay | ||
IC50 | 2.20±n/a nM | ||
Citation | ![]() | ||
More Info.: | Get all data from this article, Assay Method | ||
Non-receptor tyrosine-protein kinase TYK2 [580-1182] | |||
Name: | Non-receptor tyrosine-protein kinase TYK2 [580-1182] | ||
Synonyms: | TYK2 | TYK2 (aa 580-1182) | TYK2_HUMAN | ||
Type: | n/a | ||
Mol. Mass.: | 68754.63 | ||
Organism: | Homo sapiens (Human) | ||
Description: | P29597[580-1182] | ||
Residue: | 608 | ||
Sequence: |
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BDBM505110 | |||
n/a | |||
Name | BDBM505110 | ||
Synonyms: | US11066406, Ex. 4 | ||
Type | Small organic molecule | ||
Emp. Form. | C21H23N7O | ||
Mol. Mass. | 389.4536 | ||
SMILES | O=C(Cc1nc2cnc3[nH]ccc3c2n1C1CCC(CC#N)CC1)NCCC#N |(2.71,-11.42,;2.71,-9.88,;4.05,-9.11,;5.38,-9.88,;5.54,-11.41,;7.05,-11.73,;7.82,-13.06,;9.36,-13.06,;10.13,-11.73,;11.63,-11.41,;11.8,-9.88,;10.39,-9.25,;9.36,-10.39,;7.82,-10.39,;6.79,-9.25,;7.11,-7.74,;5.96,-6.71,;6.28,-5.21,;7.75,-4.73,;8.07,-3.22,;9.53,-2.75,;11,-2.27,;8.89,-5.76,;8.57,-7.27,;1.38,-9.11,;.05,-9.88,;-1.29,-9.11,;-2.62,-9.88,;-3.96,-10.65,)| | ||
Structure | ![]() |