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TargetLow molecular weight phosphotyrosine protein phosphatase
LigandBDBM533039
Substrate/Competitorn/a
Meas. Tech.LMPTP Primary Screening Protocol
IC50 500±n/a nM
Citation Bottini, NZou, JGanji, SRStanford, SPinkerton, AChung, TDHedrick, MArdecky, R Inhibitors of low molecular weight protein tyrosine phosphatase and uses thereof US Patent US11220486 Publication Date 1/11/2022
More Info.:Get all data from this article,  Assay Method
 
Low molecular weight phosphotyrosine protein phosphatase
Name:Low molecular weight phosphotyrosine protein phosphatase
Synonyms:3.1.3.2 | 3.1.3.48 | ACP1 | Adipocyte acid phosphatase | LMW-PTP | LMW-PTPase | LMWPTP | Low molecular weight cytosolic acid phosphatase | PPAC_HUMAN | Red cell acid phosphatase 1 | low molecular weight phosphotyrosine protein phosphatase isoform c
Type:n/a
Mol. Mass.:18042.81
Organism:Homo sapiens (Human)
Description:P24666
Residue:158
Sequence:
MAEQATKSVLFVCLGNICRSPIAEAVFRKLVTDQNISENWRVDSAATSGYEIGNPPDYRG
QSCMKRHGIPMSHVARQITKEDFATFDYILCMDESNLRDLNRKSNQVKTCKAKIELLGSY
DPQKQLIIEDPYYGNDSDFETVYQQCVRCCRAFLEKAH
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BDBM533039
n/a
NameBDBM533039
Synonyms:US10626094, Example G56 | US11220486, Compound G56 | [2-(4-methoxyphenyl)(4-quinolyl)][3-(1,4- thiazaperhydroin-4-ylmethyl)phenyl]amine
TypeSmall organic molecule
Emp. Form.C27H27N3OS
Mol. Mass.441.588
SMILESCOc1ccc(cc1)-c1cc(Nc2cccc(CN3CCSCC3)c2)c2ccccc2n1
Structure
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