Compile Data Set for Download or QSAR

Found 2186 hits with Last Name = 'hedrick' and Initial = 'm'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50163152 (1-Oxazolo[4,5-b]pyridin-2-yl-octadec-9-yn-1-one | ...) Show SMILES CCCCCCCCC#CCCCCCCCC(=O)c1nc2ncccc2o1 Show InChI InChI=1S/C24H34N2O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-18-21(27)24-26-23-22(28-24)19-17-20-25-23/h17,19-20H,2-8,11-16,18H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.140	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibitory constant determined against recombinant Fatty-acid amide hydrolase from rat expressed in Escherichia coli				J Med Chem 48: 1849-56 (2005) Article DOI: 10.1021/jm049614v BindingDB Entry DOI: 10.7270/Q2Q52P54
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50161518 (1-(oxazolo[4,5-b]pyridin-2-yl)-6-phenylhexan-1-one...) Show SMILES O=C(CCCCCc1ccccc1)c1nc2ncccc2o1 Show InChI InChI=1S/C18H18N2O2/c21-15(18-20-17-16(22-18)12-7-13-19-17)11-6-2-5-10-14-8-3-1-4-9-14/h1,3-4,7-9,12-13H,2,5-6,10-11H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.200	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibitory constant determined against recombinant Fatty-acid amide hydrolase from rat expressed in Escherichia coli				J Med Chem 48: 1849-56 (2005) Article DOI: 10.1021/jm049614v BindingDB Entry DOI: 10.7270/Q2Q52P54
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM23316 (7-phenyl-1-{pyrido[2,3-d][1,3]oxazol-2-yl}heptan-1...) Show SMILES O=C(CCCCCCc1ccccc1)c1nc2ncccc2o1 Show InChI InChI=1S/C19H20N2O2/c22-16(19-21-18-17(23-19)13-8-14-20-18)12-7-2-1-4-9-15-10-5-3-6-11-15/h3,5-6,8,10-11,13-14H,1-2,4,7,9,12H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	0.280	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibitory constant determined against recombinant Fatty-acid amide hydrolase from rat expressed in Escherichia coli				J Med Chem 48: 1849-56 (2005) Article DOI: 10.1021/jm049614v BindingDB Entry DOI: 10.7270/Q2Q52P54
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50297852 (2-(4-(1H-imidazol-1-yl)piperidin-1-yl)-1-(4-fluoro...) Show SMILES Fc1ccc(Cn2c(nc3ccccc23)N2CCC(CC2)n2ccnc2)cc1 Show InChI InChI=1S/C22H22FN5/c23-18-7-5-17(6-8-18)15-28-21-4-2-1-3-20(21)25-22(28)26-12-9-19(10-13-26)27-14-11-24-16-27/h1-8,11,14,16,19H,9-10,12-13,15H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assay				Bioorg Med Chem Lett 19: 4380-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.086 BindingDB Entry DOI: 10.7270/Q2KS6RM8
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50297863 (CHEMBL563451 | N,N-dimethyl-1-(1-(4-methylbenzyl)-...) Show SMILES CN(C)C1CCN(CC1)c1nc2ccccc2n1Cc1ccc(C)cc1 Show InChI InChI=1S/C22H28N4/c1-17-8-10-18(11-9-17)16-26-21-7-5-4-6-20(21)23-22(26)25-14-12-19(13-15-25)24(2)3/h4-11,19H,12-16H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assay				Bioorg Med Chem Lett 19: 4380-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.086 BindingDB Entry DOI: 10.7270/Q2KS6RM8
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50297864 (1-(1-(4-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)-N,...) Show SMILES CN(C)C1CCN(CC1)c1nc2ccccc2n1Cc1ccc(F)cc1 Show InChI InChI=1S/C21H25FN4/c1-24(2)18-11-13-25(14-12-18)21-23-19-5-3-4-6-20(19)26(21)15-16-7-9-17(22)10-8-16/h3-10,18H,11-15H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assay				Bioorg Med Chem Lett 19: 4380-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.086 BindingDB Entry DOI: 10.7270/Q2KS6RM8
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50163165 (1-(5-(pyridin-2-yl)oxazol-2-yl)dodecan-1-one | 1-(...) Show SMILES CCCCCCCCCCCC(=O)c1ncc(o1)-c1ccccn1 Show InChI InChI=1S/C20H28N2O2/c1-2-3-4-5-6-7-8-9-10-14-18(23)20-22-16-19(24-20)17-13-11-12-15-21-17/h11-13,15-16H,2-10,14H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibitory constant determined against recombinant Fatty-acid amide hydrolase from rat expressed in Escherichia coli				J Med Chem 48: 1849-56 (2005) Article DOI: 10.1021/jm049614v BindingDB Entry DOI: 10.7270/Q2Q52P54
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50297859 (1-(1-(4-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)-N-...) Show SMILES COCCN(C)C1CCN(CC1)c1nc2ccccc2n1Cc1ccc(F)cc1 Show InChI InChI=1S/C23H29FN4O/c1-26(15-16-29-2)20-11-13-27(14-12-20)23-25-21-5-3-4-6-22(21)28(23)17-18-7-9-19(24)10-8-18/h3-10,20H,11-17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assay				Bioorg Med Chem Lett 19: 4380-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.086 BindingDB Entry DOI: 10.7270/Q2KS6RM8
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50100865 ((Z)-1-(oxazolo[4,5-b]pyridin-2-yl)octadec-9-en-1-o...) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)c1nc2ncccc2o1 Show InChI InChI=1S/C24H36N2O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-18-21(27)24-26-23-22(28-24)19-17-20-25-23/h9-10,17,19-20H,2-8,11-16,18H2,1H3/b10-9-	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against fatty acid amide hydrolase (FAAH)				Bioorg Med Chem Lett 11: 1517-20 (2001) BindingDB Entry DOI: 10.7270/Q2NG4PWS
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50163177 (7-Phenyl-1-(5-pyrimidin-4-yl-oxazol-2-yl)-heptan-1...) Show SMILES O=C(CCCCCCc1ccccc1)c1ncc(o1)-c1ccncn1 Show InChI InChI=1S/C20H21N3O2/c24-18(11-7-2-1-4-8-16-9-5-3-6-10-16)20-22-14-19(25-20)17-12-13-21-15-23-17/h3,5-6,9-10,12-15H,1-2,4,7-8,11H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibitory constant determined against recombinant Fatty-acid amide hydrolase from rat expressed in Escherichia coli				J Med Chem 48: 1849-56 (2005) Article DOI: 10.1021/jm049614v BindingDB Entry DOI: 10.7270/Q2Q52P54
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50297862 (1-(1-(4-methoxybenzyl)-1H-benzo[d]imidazol-2-yl)-N...) Show SMILES COc1ccc(Cn2c(nc3ccccc23)N2CCC(CC2)N(C)C)cc1 Show InChI InChI=1S/C22H28N4O/c1-24(2)18-12-14-25(15-13-18)22-23-20-6-4-5-7-21(20)26(22)16-17-8-10-19(27-3)11-9-17/h4-11,18H,12-16H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assay				Bioorg Med Chem Lett 19: 4380-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.086 BindingDB Entry DOI: 10.7270/Q2KS6RM8
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50297869 (1-(1-(4-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)-N-...) Show SMILES CN(CCc1ccccc1)C1CCN(CC1)c1nc2ccccc2n1Cc1ccc(F)cc1 Show InChI InChI=1S/C28H31FN4/c1-31(18-15-22-7-3-2-4-8-22)25-16-19-32(20-17-25)28-30-26-9-5-6-10-27(26)33(28)21-23-11-13-24(29)14-12-23/h2-14,25H,15-21H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assay				Bioorg Med Chem Lett 19: 4380-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.086 BindingDB Entry DOI: 10.7270/Q2KS6RM8
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50297866 (1-(1-(4-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)-N-...) Show SMILES CNC1CCN(CC1)c1nc2ccccc2n1Cc1ccc(F)cc1 Show InChI InChI=1S/C20H23FN4/c1-22-17-10-12-24(13-11-17)20-23-18-4-2-3-5-19(18)25(20)14-15-6-8-16(21)9-7-15/h2-9,17,22H,10-14H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	2.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assay				Bioorg Med Chem Lett 19: 4380-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.086 BindingDB Entry DOI: 10.7270/Q2KS6RM8
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM22877 (2-((1-(1-(4-fluorobenzyl)-1H-benzo[d]imidazol-2-yl...) Show SMILES CN(C1CCN(CC1)c1nc2ccccc2n1Cc1ccc(F)cc1)c1nccc(=O)[nH]1 Show InChI InChI=1S/C24H25FN6O/c1-29(23-26-13-10-22(32)28-23)19-11-14-30(15-12-19)24-27-20-4-2-3-5-21(20)31(24)16-17-6-8-18(25)9-7-17/h2-10,13,19H,11-12,14-16H2,1H3,(H,26,28,32)	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Patents Similars	Article PubMed	2.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assay				Bioorg Med Chem Lett 19: 4380-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.086 BindingDB Entry DOI: 10.7270/Q2KS6RM8
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50297867 (CHEMBL558933 | N-cyclohexyl-1-(1-(4-fluorobenzyl)-...) Show SMILES CN(C1CCCCC1)C1CCN(CC1)c1nc2ccccc2n1Cc1ccc(F)cc1 Show InChI InChI=1S/C26H33FN4/c1-29(22-7-3-2-4-8-22)23-15-17-30(18-16-23)26-28-24-9-5-6-10-25(24)31(26)19-20-11-13-21(27)14-12-20/h5-6,9-14,22-23H,2-4,7-8,15-19H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assay				Bioorg Med Chem Lett 19: 4380-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.086 BindingDB Entry DOI: 10.7270/Q2KS6RM8
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50297855 (CHEMBL559061 | N1-(1-(1-(4-fluorobenzyl)-1H-benzo[...) Show SMILES CN(C)CCN(C)C1CCN(CC1)c1nc2ccccc2n1Cc1ccc(F)cc1 Show InChI InChI=1S/C24H32FN5/c1-27(2)16-17-28(3)21-12-14-29(15-13-21)24-26-22-6-4-5-7-23(22)30(24)18-19-8-10-20(25)11-9-19/h4-11,21H,12-18H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assay				Bioorg Med Chem Lett 19: 4380-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.086 BindingDB Entry DOI: 10.7270/Q2KS6RM8
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50297858 (2-((1-(1-(4-fluorobenzyl)-1H-benzo[d]imidazol-2-yl...) Show SMILES CN(CCO)C1CCN(CC1)c1nc2ccccc2n1Cc1ccc(F)cc1 Show InChI InChI=1S/C22H27FN4O/c1-25(14-15-28)19-10-12-26(13-11-19)22-24-20-4-2-3-5-21(20)27(22)16-17-6-8-18(23)9-7-17/h2-9,19,28H,10-16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.20	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assay				Bioorg Med Chem Lett 19: 4380-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.086 BindingDB Entry DOI: 10.7270/Q2KS6RM8
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50163174 (1-(5-Pyridin-2-yl-oxazol-2-yl)-undecan-1-one | CHE...) Show SMILES CCCCCCCCCCC(=O)c1ncc(o1)-c1ccccn1 Show InChI InChI=1S/C19H26N2O2/c1-2-3-4-5-6-7-8-9-13-17(22)19-21-15-18(23-19)16-12-10-11-14-20-16/h10-12,14-15H,2-9,13H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibitory constant determined against recombinant Fatty-acid amide hydrolase from rat expressed in Escherichia coli				J Med Chem 48: 1849-56 (2005) Article DOI: 10.1021/jm049614v BindingDB Entry DOI: 10.7270/Q2Q52P54
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50297870 (CHEMBL551888 | N-benzyl-1-(1-(4-fluorobenzyl)-1H-b...) Show SMILES CN(Cc1ccccc1)C1CCN(CC1)c1nc2ccccc2n1Cc1ccc(F)cc1 Show InChI InChI=1S/C27H29FN4/c1-30(19-21-7-3-2-4-8-21)24-15-17-31(18-16-24)27-29-25-9-5-6-10-26(25)32(27)20-22-11-13-23(28)14-12-22/h2-14,24H,15-20H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assay				Bioorg Med Chem Lett 19: 4380-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.086 BindingDB Entry DOI: 10.7270/Q2KS6RM8
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50297861 (1-(1-(4-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)-N-...) Show SMILES CN(CC1CCOCC1)C1CCN(CC1)c1nc2ccccc2n1Cc1ccc(F)cc1 Show InChI InChI=1S/C26H33FN4O/c1-29(18-21-12-16-32-17-13-21)23-10-14-30(15-11-23)26-28-24-4-2-3-5-25(24)31(26)19-20-6-8-22(27)9-7-20/h2-9,21,23H,10-19H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assay				Bioorg Med Chem Lett 19: 4380-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.086 BindingDB Entry DOI: 10.7270/Q2KS6RM8
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50297857 (1-(1-(4-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)-N-...) Show SMILES Fc1ccc(Cn2c(nc3ccccc23)N2CCC(CC2)NCC2CCOCC2)cc1 Show InChI InChI=1S/C25H31FN4O/c26-21-7-5-20(6-8-21)18-30-24-4-2-1-3-23(24)28-25(30)29-13-9-22(10-14-29)27-17-19-11-15-31-16-12-19/h1-8,19,22,27H,9-18H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assay				Bioorg Med Chem Lett 19: 4380-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.086 BindingDB Entry DOI: 10.7270/Q2KS6RM8
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50163186 (1-(5-(oxazol-2-yl)oxazol-2-yl)-7-phenylheptan-1-on...) Show SMILES O=C(CCCCCCc1ccccc1)c1ncc(o1)-c1ncco1 Show InChI InChI=1S/C19H20N2O3/c22-16(18-21-14-17(24-18)19-20-12-13-23-19)11-7-2-1-4-8-15-9-5-3-6-10-15/h3,5-6,9-10,12-14H,1-2,4,7-8,11H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibitory constant determined against recombinant Fatty-acid amide hydrolase from rat expressed in Escherichia coli				J Med Chem 48: 1849-56 (2005) Article DOI: 10.1021/jm049614v BindingDB Entry DOI: 10.7270/Q2Q52P54
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50163207 (7-Phenyl-1-(5-pyrimidin-2-yl-oxazol-2-yl)-heptan-1...) Show SMILES O=C(CCCCCCc1ccccc1)c1ncc(o1)-c1ncccn1 Show InChI InChI=1S/C20H21N3O2/c24-17(12-7-2-1-4-9-16-10-5-3-6-11-16)20-23-15-18(25-20)19-21-13-8-14-22-19/h3,5-6,8,10-11,13-15H,1-2,4,7,9,12H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	4.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibitory constant determined against recombinant Fatty-acid amide hydrolase from rat expressed in Escherichia coli				J Med Chem 48: 1849-56 (2005) Article DOI: 10.1021/jm049614v BindingDB Entry DOI: 10.7270/Q2Q52P54
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM23120 (7-phenyl-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]hepta...) Show SMILES O=C(CCCCCCc1ccccc1)c1ncc(o1)-c1ccccn1 Show InChI InChI=1S/C21H22N2O2/c24-19(14-7-2-1-4-10-17-11-5-3-6-12-17)21-23-16-20(25-21)18-13-8-9-15-22-18/h3,5-6,8-9,11-13,15-16H,1-2,4,7,10,14H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	4.70	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibitory constant determined against recombinant Fatty-acid amide hydrolase from rat expressed in Escherichia coli				J Med Chem 48: 1849-56 (2005) Article DOI: 10.1021/jm049614v BindingDB Entry DOI: 10.7270/Q2Q52P54
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50163202 (7-Phenyl-1-(5-pyrazin-2-yl-oxazol-2-yl)-heptan-1-o...) Show SMILES O=C(CCCCCCc1ccccc1)c1ncc(o1)-c1cnccn1 Show InChI InChI=1S/C20H21N3O2/c24-18(11-7-2-1-4-8-16-9-5-3-6-10-16)20-23-15-19(25-20)17-14-21-12-13-22-17/h3,5-6,9-10,12-15H,1-2,4,7-8,11H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.30	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibitory constant determined against recombinant Fatty-acid amide hydrolase from rat expressed in Escherichia coli				J Med Chem 48: 1849-56 (2005) Article DOI: 10.1021/jm049614v BindingDB Entry DOI: 10.7270/Q2Q52P54
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50163213 (7-Phenyl-1-(5-pyridazin-3-yl-oxazol-2-yl)-heptan-1...) Show SMILES O=C(CCCCCCc1ccccc1)c1ncc(o1)-c1cccnn1 Show InChI InChI=1S/C20H21N3O2/c24-18(13-7-2-1-4-9-16-10-5-3-6-11-16)20-21-15-19(25-20)17-12-8-14-22-23-17/h3,5-6,8,10-12,14-15H,1-2,4,7,9,13H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibitory constant determined against recombinant Fatty-acid amide hydrolase from rat expressed in Escherichia coli				J Med Chem 48: 1849-56 (2005) Article DOI: 10.1021/jm049614v BindingDB Entry DOI: 10.7270/Q2Q52P54
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50163164 (7-Phenyl-1-(5-thiazol-2-yl-oxazol-2-yl)-heptan-1-o...) Show SMILES O=C(CCCCCCc1ccccc1)c1ncc(o1)-c1nccs1 Show InChI InChI=1S/C19H20N2O2S/c22-16(18-21-14-17(23-18)19-20-12-13-24-19)11-7-2-1-4-8-15-9-5-3-6-10-15/h3,5-6,9-10,12-14H,1-2,4,7-8,11H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibitory constant determined against recombinant Fatty-acid amide hydrolase from rat expressed in Escherichia coli				J Med Chem 48: 1849-56 (2005) Article DOI: 10.1021/jm049614v BindingDB Entry DOI: 10.7270/Q2Q52P54
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50207875 (4'-[3-(3-methoxy-phenyl)-2,4-dioxo-1-phenyl-1,3,8-...) Show SMILES COc1cccc(c1)N1C(=O)N(c2ccccc2)C2(CCN(Cc3ccc(cc3)-c3cccc(c3)C#N)CC2)C1=O Show InChI InChI=1S/C34H30N4O3/c1-41-31-12-6-11-30(22-31)37-32(39)34(38(33(37)40)29-9-3-2-4-10-29)17-19-36(20-18-34)24-25-13-15-27(16-14-25)28-8-5-7-26(21-28)23-35/h2-16,21-22H,17-20,24H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cells				Bioorg Med Chem Lett 17: 2171-8 (2007) Article DOI: 10.1016/j.bmcl.2007.01.104 BindingDB Entry DOI: 10.7270/Q20C4VF3
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50207882 (4'-(2,4-dioxo-1-phenyl-3-m-tolyl-1,3,8-triaza-spir...) Show SMILES Cc1cccc(c1)N1C(=O)N(c2ccccc2)C2(CCN(Cc3ccc(cc3)-c3cccc(c3)C#N)CC2)C1=O Show InChI InChI=1S/C34H30N4O2/c1-25-7-5-12-31(21-25)37-32(39)34(38(33(37)40)30-10-3-2-4-11-30)17-19-36(20-18-34)24-26-13-15-28(16-14-26)29-9-6-8-27(22-29)23-35/h2-16,21-22H,17-20,24H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cells				Bioorg Med Chem Lett 17: 2171-8 (2007) Article DOI: 10.1016/j.bmcl.2007.01.104 BindingDB Entry DOI: 10.7270/Q20C4VF3
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50297854 (1'-(1-(4-fluorobenzyl)-1H-benzo[d]imidazol-2-yl)-1...) Show SMILES Fc1ccc(Cn2c(nc3ccccc23)N2CCC(CC2)N2CCCCC2=O)cc1 Show InChI InChI=1S/C24H27FN4O/c25-19-10-8-18(9-11-19)17-29-22-6-2-1-5-21(22)26-24(29)27-15-12-20(13-16-27)28-14-4-3-7-23(28)30/h1-2,5-6,8-11,20H,3-4,7,12-17H2	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.60	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assay				Bioorg Med Chem Lett 19: 4380-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.086 BindingDB Entry DOI: 10.7270/Q2KS6RM8
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50297850 (1-(4-fluorobenzyl)-2-(4-(4-methyl-1H-pyrazol-1-yl)...) Show SMILES Cc1cnn(c1)C1CCN(CC1)c1nc2ccccc2n1Cc1ccc(F)cc1 Show InChI InChI=1S/C23H24FN5/c1-17-14-25-29(15-17)20-10-12-27(13-11-20)23-26-21-4-2-3-5-22(21)28(23)16-18-6-8-19(24)9-7-18/h2-9,14-15,20H,10-13,16H2,1H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase CHEMBL MCE PC cid PC sid UniChem Similars	Article PubMed	6.90	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assay				Bioorg Med Chem Lett 19: 4380-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.086 BindingDB Entry DOI: 10.7270/Q2KS6RM8
					More data for this Ligand-Target Pair
Histamine H1 receptor (Homo sapiens (Human))	BDBM50297849 (1-(4-methoxybenzyl)-2-(4-(4-methyl-1H-pyrazol-1-yl...) Show SMILES COc1ccc(Cn2c(nc3ccccc23)N2CCC(CC2)n2cc(C)cn2)cc1 Show InChI InChI=1S/C24H27N5O/c1-18-15-25-29(16-18)20-11-13-27(14-12-20)24-26-22-5-3-4-6-23(22)28(24)17-19-7-9-21(30-2)10-8-19/h3-10,15-16,20H,11-14,17H2,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Curated by ChEMBL					Assay Description Displacement of [3H]pyrilamine from human histamine H1 receptor expressed in CHO Flp-In cells by liquid scintillation assay				Bioorg Med Chem Lett 19: 4380-4 (2009) Article DOI: 10.1016/j.bmcl.2009.05.086 BindingDB Entry DOI: 10.7270/Q2KS6RM8
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50161519 (8-Phenyl-1-(5-pyridin-2-yl-oxazol-2-yl)-octan-1-on...) Show SMILES O=C(CCCCCCCc1ccccc1)c1ncc(o1)-c1ccccn1 Show InChI InChI=1S/C22H24N2O2/c25-20(22-24-17-21(26-22)19-14-9-10-16-23-19)15-8-3-1-2-5-11-18-12-6-4-7-13-18/h4,6-7,9-10,12-14,16-17H,1-3,5,8,11,15H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibitory constant determined against recombinant Fatty-acid amide hydrolase from rat expressed in Escherichia coli				J Med Chem 48: 1849-56 (2005) Article DOI: 10.1021/jm049614v BindingDB Entry DOI: 10.7270/Q2Q52P54
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50161523 (9-Phenyl-1-(5-pyridin-2-yl-oxazol-2-yl)-nonan-1-on...) Show SMILES O=C(CCCCCCCCc1ccccc1)c1ncc(o1)-c1ccccn1 Show InChI InChI=1S/C23H26N2O2/c26-21(23-25-18-22(27-23)20-15-10-11-17-24-20)16-9-4-2-1-3-6-12-19-13-7-5-8-14-19/h5,7-8,10-11,13-15,17-18H,1-4,6,9,12,16H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	7.80	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibitory constant determined against recombinant Fatty-acid amide hydrolase from rat expressed in Escherichia coli				J Med Chem 48: 1849-56 (2005) Article DOI: 10.1021/jm049614v BindingDB Entry DOI: 10.7270/Q2Q52P54
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50207867 (1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-8-[4-(4-m...) Show SMILES COc1cccc(c1)N1C(=O)N(Cc2ccccc2F)C2(CCN(Cc3ccc(cc3)-c3cnccc3OC)CC2)C1=O Show InChI InChI=1S/C34H33FN4O4/c1-42-28-8-5-7-27(20-28)39-32(40)34(38(33(39)41)23-26-6-3-4-9-30(26)35)15-18-37(19-16-34)22-24-10-12-25(13-11-24)29-21-36-17-14-31(29)43-2/h3-14,17,20-21H,15-16,18-19,22-23H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cells				Bioorg Med Chem Lett 17: 2171-8 (2007) Article DOI: 10.1016/j.bmcl.2007.01.104 BindingDB Entry DOI: 10.7270/Q20C4VF3
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50207891 (5-chloro-4'-(2,4-dioxo-1-phenyl-1,3,8-triaza-spiro...) Show SMILES Clc1cc(cc(c1)-c1ccc(CN2CCC3(CC2)N(C(=O)NC3=O)c2ccccc2)cc1)C#N Show InChI InChI=1S/C27H23ClN4O2/c28-23-15-20(17-29)14-22(16-23)21-8-6-19(7-9-21)18-31-12-10-27(11-13-31)25(33)30-26(34)32(27)24-4-2-1-3-5-24/h1-9,14-16H,10-13,18H2,(H,30,33,34)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	8	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cells				Bioorg Med Chem Lett 17: 2171-8 (2007) Article DOI: 10.1016/j.bmcl.2007.01.104 BindingDB Entry DOI: 10.7270/Q20C4VF3
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50163167 (1-(5-Pyridin-2-yl-oxazol-2-yl)-decan-1-one | CHEMB...) Show SMILES CCCCCCCCCC(=O)c1ncc(o1)-c1ccccn1 Show InChI InChI=1S/C18H24N2O2/c1-2-3-4-5-6-7-8-12-16(21)18-20-14-17(22-18)15-11-9-10-13-19-15/h9-11,13-14H,2-8,12H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibitory constant determined against recombinant Fatty-acid amide hydrolase from rat expressed in Escherichia coli				J Med Chem 48: 1849-56 (2005) Article DOI: 10.1021/jm049614v BindingDB Entry DOI: 10.7270/Q2Q52P54
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM23120 (7-phenyl-1-[5-(pyridin-2-yl)-1,3-oxazol-2-yl]hepta...) Show SMILES O=C(CCCCCCc1ccccc1)c1ncc(o1)-c1ccccn1 Show InChI InChI=1S/C21H22N2O2/c24-19(14-7-2-1-4-10-17-11-5-3-6-12-17)21-23-16-20(25-21)18-13-8-9-15-22-18/h3,5-6,8-9,11-13,15-16H,1-2,4,7,10,14H2	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibitory constant determined against recombinant Fatty-acid amide hydrolase from human expressed in COS-7 cells				J Med Chem 48: 1849-56 (2005) Article DOI: 10.1021/jm049614v BindingDB Entry DOI: 10.7270/Q2Q52P54
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50100873 ((Z)-2-Methyl-1-oxazolo[5,4-b]pyridin-2-yl-octadec-...) Show SMILES CCCCCCCC\C=C/CCCCCCC(C)C(=O)c1nc2cccnc2o1 Show InChI InChI=1S/C25H38N2O2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-18-21(2)23(28)25-27-22-19-17-20-26-24(22)29-25/h10-11,17,19-21H,3-9,12-16,18H2,1-2H3/b11-10-	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	9.10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibitory activity against fatty acid amide hydrolase (FAAH)				Bioorg Med Chem Lett 11: 1517-20 (2001) BindingDB Entry DOI: 10.7270/Q2NG4PWS
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50163156 (10-Phenyl-1-(5-pyridin-2-yl-oxazol-2-yl)-decan-1-o...) Show SMILES O=C(CCCCCCCCCc1ccccc1)c1ncc(o1)-c1ccccn1 Show InChI InChI=1S/C24H28N2O2/c27-22(24-26-19-23(28-24)21-16-11-12-18-25-21)17-10-5-3-1-2-4-7-13-20-14-8-6-9-15-20/h6,8-9,11-12,14-16,18-19H,1-5,7,10,13,17H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibitory constant determined against recombinant Fatty-acid amide hydrolase from rat expressed in Escherichia coli				J Med Chem 48: 1849-56 (2005) Article DOI: 10.1021/jm049614v BindingDB Entry DOI: 10.7270/Q2Q52P54
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 (Homo sapiens (Human))	BDBM50157122 ((Z)-1-(5-(pyridin-2-yl)oxazol-2-yl)octadec-9-en-1-...) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)c1ncc(o1)-c1ccccn1 Show InChI InChI=1S/C26H38N2O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20-24(29)26-28-22-25(30-26)23-19-17-18-21-27-23/h9-10,17-19,21-22H,2-8,11-16,20H2,1H3/b10-9-	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibitory constant determined against recombinant Fatty-acid amide hydrolase from human expressed in COS-7 cells				J Med Chem 48: 1849-56 (2005) Article DOI: 10.1021/jm049614v BindingDB Entry DOI: 10.7270/Q2Q52P54
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50207885 (5-{4-[1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-2,4...) Show SMILES COc1cccc(c1)N1C(=O)N(Cc2ccccc2F)C2(CCN(Cc3ccc(cc3)-c3cncc(c3)C#N)CC2)C1=O Show InChI InChI=1S/C34H30FN5O3/c1-43-30-7-4-6-29(18-30)40-32(41)34(39(33(40)42)23-27-5-2-3-8-31(27)35)13-15-38(16-14-34)22-24-9-11-26(12-10-24)28-17-25(19-36)20-37-21-28/h2-12,17-18,20-21H,13-16,22-23H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cells				Bioorg Med Chem Lett 17: 2171-8 (2007) Article DOI: 10.1016/j.bmcl.2007.01.104 BindingDB Entry DOI: 10.7270/Q20C4VF3
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50163159 (1-(5-Pyridin-2-yl-oxazol-2-yl)-octadec-9-yn-1-one ...) Show SMILES CCCCCCCCC#CCCCCCCCC(=O)c1ncc(o1)-c1ccccn1 Show InChI InChI=1S/C26H36N2O2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20-24(29)26-28-22-25(30-26)23-19-17-18-21-27-23/h17-19,21-22H,2-8,11-16,20H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	10	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibitory constant determined against recombinant Fatty-acid amide hydrolase from rat expressed in Escherichia coli				J Med Chem 48: 1849-56 (2005) Article DOI: 10.1021/jm049614v BindingDB Entry DOI: 10.7270/Q2Q52P54
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50163157 (1-(5-Pyridin-2-yl-oxazol-2-yl)-dec-9-en-1-one | CH...) Show SMILES C=CCCCCCCCC(=O)c1ncc(o1)-c1ccccn1 Show InChI InChI=1S/C18H22N2O2/c1-2-3-4-5-6-7-8-12-16(21)18-20-14-17(22-18)15-11-9-10-13-19-15/h2,9-11,13-14H,1,3-8,12H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibitory constant determined against recombinant Fatty-acid amide hydrolase from rat expressed in Escherichia coli				J Med Chem 48: 1849-56 (2005) Article DOI: 10.1021/jm049614v BindingDB Entry DOI: 10.7270/Q2Q52P54
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50161517 (6-Phenyl-1-(5-pyridin-2-yl-oxazol-2-yl)-hexan-1-on...) Show SMILES O=C(CCCCCc1ccccc1)c1ncc(o1)-c1ccccn1 Show InChI InChI=1S/C20H20N2O2/c23-18(13-6-2-5-11-16-9-3-1-4-10-16)20-22-15-19(24-20)17-12-7-8-14-21-17/h1,3-4,7-10,12,14-15H,2,5-6,11,13H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	11	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibitory constant determined against recombinant Fatty-acid amide hydrolase from rat expressed in Escherichia coli				J Med Chem 48: 1849-56 (2005) Article DOI: 10.1021/jm049614v BindingDB Entry DOI: 10.7270/Q2Q52P54
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50207864 (4'-[1-cyclohexyl-3-(3-methoxy-phenyl)-2,4-dioxo-1,...) Show SMILES COc1cccc(c1)N1C(=O)N(C2CCCCC2)C2(CCN(Cc3ccc(cc3)-c3cccc(c3)C#N)CC2)C1=O Show InChI InChI=1S/C34H36N4O3/c1-41-31-12-6-11-30(22-31)37-32(39)34(38(33(37)40)29-9-3-2-4-10-29)17-19-36(20-18-34)24-25-13-15-27(16-14-25)28-8-5-7-26(21-28)23-35/h5-8,11-16,21-22,29H,2-4,9-10,17-20,24H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cells				Bioorg Med Chem Lett 17: 2171-8 (2007) Article DOI: 10.1016/j.bmcl.2007.01.104 BindingDB Entry DOI: 10.7270/Q20C4VF3
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50163180 ((Z)-1-(5-(oxazol-2-yl)oxazol-2-yl)octadec-9-en-1-o...) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)c1ncc(o1)-c1ncco1 Show InChI InChI=1S/C24H36N2O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(27)23-26-20-22(29-23)24-25-18-19-28-24/h9-10,18-20H,2-8,11-17H2,1H3/b10-9-	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibitory constant determined against recombinant Fatty-acid amide hydrolase from rat expressed in Escherichia coli				J Med Chem 48: 1849-56 (2005) Article DOI: 10.1021/jm049614v BindingDB Entry DOI: 10.7270/Q2Q52P54
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50157136 (1-(5-(furan-2-yl)oxazol-2-yl)-7-phenylheptan-1-one...) Show SMILES O=C(CCCCCCc1ccccc1)c1ncc(o1)-c1ccco1 Show InChI InChI=1S/C20H21NO3/c22-17(20-21-15-19(24-20)18-13-8-14-23-18)12-7-2-1-4-9-16-10-5-3-6-11-16/h3,5-6,8,10-11,13-15H,1-2,4,7,9,12H2	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	12	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibitory constant determined against recombinant Fatty-acid amide hydrolase from rat expressed in Escherichia coli				J Med Chem 48: 1849-56 (2005) Article DOI: 10.1021/jm049614v BindingDB Entry DOI: 10.7270/Q2Q52P54
					More data for this Ligand-Target Pair
Melanin-concentrating hormone receptor 1 (Homo sapiens (Human))	BDBM50207884 (1-(2-fluoro-benzyl)-3-(3-methoxy-phenyl)-8-[4-(5-m...) Show SMILES COc1cccc(c1)N1C(=O)N(Cc2ccccc2F)C2(CCN(Cc3ccc(cc3)-c3cncc(OC)c3)CC2)C1=O Show InChI InChI=1S/C34H33FN4O4/c1-42-29-8-5-7-28(19-29)39-32(40)34(38(33(39)41)23-26-6-3-4-9-31(26)35)14-16-37(17-15-34)22-24-10-12-25(13-11-24)27-18-30(43-2)21-36-20-27/h3-13,18-21H,14-17,22-23H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Neurocrine Biosciences Inc. Curated by ChEMBL					Assay Description Displacement of [125I-Tyr13] from human MCH-R1 expressed in HEK 293 cells				Bioorg Med Chem Lett 17: 2171-8 (2007) Article DOI: 10.1016/j.bmcl.2007.01.104 BindingDB Entry DOI: 10.7270/Q20C4VF3
					More data for this Ligand-Target Pair
Fatty-acid amide hydrolase 1 [30-579] (Rattus norvegicus (rat))	BDBM50163168 (1-(5-Pyridin-2-yl-oxazol-2-yl)-tetradecan-1-one | ...) Show SMILES CCCCCCCCCCCCCC(=O)c1ncc(o1)-c1ccccn1 Show InChI InChI=1S/C22H32N2O2/c1-2-3-4-5-6-7-8-9-10-11-12-16-20(25)22-24-18-21(26-22)19-15-13-14-17-23-19/h13-15,17-18H,2-12,16H2,1H3	PDB MMDB UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	13	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibitory constant determined against recombinant Fatty-acid amide hydrolase from rat expressed in Escherichia coli				J Med Chem 48: 1849-56 (2005) Article DOI: 10.1021/jm049614v BindingDB Entry DOI: 10.7270/Q2Q52P54
					More data for this Ligand-Target Pair

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