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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Growth arrest-specific protein 6 | ||
| Ligand | BDBM50444249 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Activity Assay | ||
| IC50 | 658±n/a nM | ||
| Citation |  Wang, X; Zhang, W; Frye, S Therapeutic uses of selected pyrimidine compounds with anti-Mer tyrosine kinase activity US Patent US9649309 Publication Date 5/16/2017 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Growth arrest-specific protein 6 | |||
| Name: | Growth arrest-specific protein 6 | ||
| Synonyms: | AXL receptor tyrosine kinase ligand | AXLLG | GAS-6 | GAS6 | GAS6_HUMAN | ||
| Type: | PROTEIN | ||
| Mol. Mass.: | 74914.43 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | Q14393 | ||
| Residue: | 678 | ||
| Sequence: |
| ||
| BDBM50444249 | |||
| n/a | |||
| Name | BDBM50444249 | ||
| Synonyms: | CHEMBL3093748 | US9649309, Compound UNC2776A | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H31N5O3 | ||
| Mol. Mass. | 413.5132 | ||
| SMILES | CCCCNc1ncc(C(=O)Nc2ccc(OC)cc2)c(N[C@H]2CC[C@H](O)CC2)n1 |r,wU:22.22,wD:25.26,(20.21,-47.13,;21.55,-46.36,;22.88,-47.13,;24.21,-46.36,;25.55,-47.13,;26.88,-46.37,;28.22,-47.14,;29.55,-46.36,;29.55,-44.81,;30.88,-44.04,;30.87,-42.5,;32.22,-44.8,;33.55,-44.03,;34.88,-44.8,;36.21,-44.03,;36.2,-42.49,;37.53,-41.71,;38.87,-42.47,;34.86,-41.72,;33.53,-42.5,;28.21,-44.05,;28.21,-42.51,;26.87,-41.74,;25.54,-42.52,;24.2,-41.75,;24.2,-40.21,;22.87,-39.44,;25.54,-39.44,;26.86,-40.21,;26.88,-44.82,)| | ||
| Structure | 
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