| Reaction Details |
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 | Report a problem with these data |
| Target | Integrin-linked protein kinase |
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| Ligand | BDBM582529 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Biochemical Assay |
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| Kd | 1546±n/a nM |
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| Citation |  Qin, J; Fukuda, K; Vaynberg, J; Rachakonda, S Compounds for treating ILK-mediated diseases US Patent US11524945 Publication Date 12/13/2022 |
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| More Info.: | Get all data from this article, Assay Method |
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| Integrin-linked protein kinase |
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| Name: | Integrin-linked protein kinase |
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| Synonyms: | ILK | ILK1 | ILK2 | ILK_HUMAN | Integrin-linked protein kinase (ILK) | Serine/threonine-protein kinase ILK-1 |
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| Type: | Protein |
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| Mol. Mass.: | 51429.75 |
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| Organism: | Homo sapiens (Human) |
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| Description: | Q13418 |
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| Residue: | 452 |
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| Sequence: | MDDIFTQCREGNAVAVRLWLDNTENDLNQGDDHGFSPLHWACREGRSAVVEMLIMRGARI
NVMNRGDDTPLHLAASHGHRDIVQKLLQYKADINAVNEHGNVPLHYACFWGQDQVAEDLV
ANGALVSICNKYGEMPVDKAKAPLRELLRERAEKMGQNLNRIPYKDTFWKGTTRTRPRNG
TLNKHSGIDFKQLNFLTKLNENHSGELWKGRWQGNDIVVKVLKVRDWSTRKSRDFNEECP
RLRIFSHPNVLPVLGACQSPPAPHPTLITHWMPYGSLYNVLHEGTNFVVDQSQAVKFALD
MARGMAFLHTLEPLIPRHALNSRSVMIDEDMTARISMADVKFSFQCPGRMYAPAWVAPEA
LQKKPEDTNRRSADMWSFAVLLWELVTREVPFADLSNMEIGMKVALEGLRPTIPPGISPH
VCKLMKICMNEDPAKRPKFDMIVPILEKMQDK
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|
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| BDBM582529 |
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| n/a |
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| Name | BDBM582529 |
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| Synonyms: | US11524945, Compound Erlotinib-4-methylphenyl analog (E4ME) |
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| Type | Small organic molecule |
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| Emp. Form. | C23H25N3O4 |
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| Mol. Mass. | 407.4623 |
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| SMILES | COCCOc1cc2ncnc(Nc3ccc(C)c(c3)C#C)c2cc1OCCOC |
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| Structure | 
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