| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Casein kinase I isoform delta |
|---|
| Ligand | BDBM629083 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Enzyme Assay |
|---|
| IC50 | 372±n/a nM |
|---|
| Citation |  Lebold, TP; McCarver, S; McClure, KJ; Preville, C; Seierstad, M; Shireman, BT; Wang, J; Wu, D; Zhang, W; Ziff, JM CASEIN KINASE 1 DELTA MODULATORS US Patent US20230339900 Publication Date 10/26/2023 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Casein kinase I isoform delta |
|---|
| Name: | Casein kinase I isoform delta |
|---|
| Synonyms: | CKI-delta | CKId | CSNK1D | Casein kinase 1 delta (CK1δ) | Casein kinase I delta | Casein kinase I isoform alpha/delta | Casein kinase I isoform delta (CK1D) | HCKID | KC1D_HUMAN | casein kinases 1 delta (CK1 delta) |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 47356.76 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | P48730 |
|---|
| Residue: | 415 |
|---|
| Sequence: | MELRVGNRYRLGRKIGSGSFGDIYLGTDIAAGEEVAIKLECVKTKHPQLHIESKIYKMMQ
GGVGIPTIRWCGAEGDYNVMVMELLGPSLEDLFNFCSRKFSLKTVLLLADQMISRIEYIH
SKNFIHRDVKPDNFLMGLGKKGNLVYIIDFGLAKKYRDARTHQHIPYRENKNLTGTARYA
SINTHLGIEQSRRDDLESLGYVLMYFNLGSLPWQGLKAATKRQKYERISEKKMSTPIEVL
CKGYPSEFATYLNFCRSLRFDDKPDYSYLRQLFRNLFHRQGFSYDYVFDWNMLKFGASRA
ADDAERERRDREERLRHSRNPATRGLPSTASGRLRGTQEVAPPTPLTPTSHTANTSPRPV
SGMERERKVSMRLHRGAPVNISSSDLTGRQDTSRMSTSQIPGRVASSGLQSVVHR
|
|
|
|---|
| BDBM629083 |
|---|
| n/a |
|---|
| Name | BDBM629083 |
|---|
| Synonyms: | 4-(3-(5-Fluoropyridin-2-yl)-1-isopropyl-1H-pyrazol-4-yl)-6-methyl-1H- | US20230339900, Example 60 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C18H17FN6 |
|---|
| Mol. Mass. | 336.3662 |
|---|
| SMILES | CC(C)n1cc(c(n1)-c1ccc(F)cn1)-c1cc(C)nc2[nH]ncc12 |
|---|
| Structure | 
|
|---|
Search and Browse
