| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Retinoic acid receptor RXR-alpha |
|---|
| Ligand | BDBM323588 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | Retinoid Nuclear Receptor Activity |
|---|
| EC50 | 316±n/a nM |
|---|
| Citation |  Scott, IL; Kuksa, VA; Orme, MW; Little, Jr., TL; Gall, A; Hong, F Alkoxy compounds for disease treatment US Patent US10188615 Publication Date 1/29/2019 |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Retinoic acid receptor RXR-alpha |
|---|
| Name: | Retinoic acid receptor RXR-alpha |
|---|
| Synonyms: | NR2B1 | Nuclear receptor subfamily 2 group B member 1 | Nuclear receptor subfamily 4 group A member 2 | Nuclear receptor subfamily 4 group A member 2/Retinoic acid receptor RXR-alpha | RXRA | RXRA_HUMAN | Retinoic acid receptor RXR-alpha/gamma | Retinoid X receptor alpha | Retinoid receptor |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 50820.38 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_1456363 |
|---|
| Residue: | 462 |
|---|
| Sequence: | MDTKHFLPLDFSTQVNSSLTSPTGRGSMAAPSLHPSLGPGIGSPGQLHSPISTLSSPING
MGPPFSVISSPMGPHSMSVPTTPTLGFSTGSPQLSSPMNPVSSSEDIKPPLGLNGVLKVP
AHPSGNMASFTKHICAICGDRSSGKHYGVYSCEGCKGFFKRTVRKDLTYTCRDNKDCLID
KRQRNRCQYCRYQKCLAMGMKREAVQEERQRGKDRNENEVESTSSANEDMPVERILEAEL
AVEPKTETYVEANMGLNPSSPNDPVTNICQAADKQLFTLVEWAKRIPHFSELPLDDQVIL
LRAGWNELLIASFSHRSIAVKDGILLATGLHVHRNSAHSAGVGAIFDRVLTELVSKMRDM
QMDKTELGCLRAIVLFNPDSKGLSNPAEVEALREKVYASLEAYCKHKYPEQPGRFAKLLL
RLPALRSIGLKCLEHLFFFKLIGDTPIDTFLMEMLEAPHQMT
|
|
|
|---|
| BDBM323588 |
|---|
| n/a |
|---|
| Name | BDBM323588 |
|---|
| Synonyms: | Retinoic Acid | US10188615, at-RA | US10752616, Code No. atRA | all-trans-retinoic acid | at-RA |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C20H28O2 |
|---|
| Mol. Mass. | 300.4351 |
|---|
| SMILES | CC(C=CC1=C(C)CCCC1(C)C)=CC=CC(C)=CC(O)=O |w:3.3,13.14,15.16,18.19,c:4| |
|---|
| Structure | 
|
|---|
Search and Browse
