| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Dipeptidyl peptidase 9 |
|---|
| Ligand | BDBM11975 |
|---|
| Substrate/Competitor | BDBM11057 |
|---|
| Meas. Tech. | Dipeptidyl Peptidase Inhibition Assay |
|---|
| IC50 | >100000±n/a nM |
|---|
| Citation |  Ashton, WT; Sisco, RM; Dong, H; Lyons, KA; He, H; Doss, GA; Leiting, B; Patel, RA; Wu, JK; Marsilio, F; Thornberry, NA; Weber, AE Dipeptidyl peptidase IV inhibitors derived from beta-aminoacylpiperidines bearing a fused thiazole, oxazole, isoxazole, or pyrazole. Bioorg Med Chem Lett15:2253-8 (2005) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Solution Info, Assay Method |
|---|
| |
| Dipeptidyl peptidase 9 |
|---|
| Name: | Dipeptidyl peptidase 9 |
|---|
| Synonyms: | DPP9 | DPP9_HUMAN | DPRP-2 | DPRP2 | Dipeptidyl peptidase 9 (DDP9) | Dipeptidyl peptidase 9 (DPP-9) | Dipeptidyl peptidase 9 (DPP9) | Dipeptidyl peptidase IV-related protein 2 | Dipeptidyl peptidase IX | Dipeptidyl peptidase IX (DDP-IX) | Dipeptidyl peptidase-like protein 9 |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 98260.70 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | Q86TI2 |
|---|
| Residue: | 863 |
|---|
| Sequence: | MATTGTPTADRGDAAATDDPAARFQVQKHSWDGLRSIIHGSRKYSGLIVNKAPHDFQFVQ
KTDESGPHSHRLYYLGMPYGSRENSLLYSEIPKKVRKEALLLLSWKQMLDHFQATPHHGV
YSREEELLRERKRLGVFGITSYDFHSESGLFLFQASNSLFHCRDGGKNGFMVSPMKPLEI
KTQCSGPRMDPKICPADPAFFSFINNSDLWVANIETGEERRLTFCHQGLSNVLDDPKSAG
VATFVIQEEFDRFTGYWWCPTASWEGSEGLKTLRILYEEVDESEVEVIHVPSPALEERKT
DSYRYPRTGSKNPKIALKLAEFQTDSQGKIVSTQEKELVQPFSSLFPKVEYIARAGWTRD
GKYAWAMFLDRPQQWLQLVLLPPALFIPSTENEEQRLASARAVPRNVQPYVVYEEVTNVW
INVHDIFYPFPQSEGEDELCFLRANECKTGFCHLYKVTAVLKSQGYDWSEPFSPGEDEFK
CPIKEEIALTSGEWEVLARHGSKIWVNEETKLVYFQGTKDTPLEHHLYVVSYEAAGEIVR
LTTPGFSHSCSMSQNFDMFVSHYSSVSTPPCVHVYKLSGPDDDPLHKQPRFWASMMEAAS
CPPDYVPPEIFHFHTRSDVRLYGMIYKPHALQPGKKHPTVLFVYGGPQVQLVNNSFKGIK
YLRLNTLASLGYAVVVIDGRGSCQRGLRFEGALKNQMGQVEIEDQVEGLQFVAEKYGFID
LSRVAIHGWSYGGFLSLMGLIHKPQVFKVAIAGAPVTVWMAYDTGYTERYMDVPENNQHG
YEAGSVALHVEKLPNEPNRLLILHGFLDENVHFFHTNFLVSQLIRAGKPYQLQIYPNERH
SIRCPESGEHYEVTLLHFLQEYL
|
|
|
|---|
| BDBM11975 |
|---|
| BDBM11057 |
|---|
| Name | BDBM11975 |
|---|
| Synonyms: | (3R)-3-amino-1-{2-cyclopropyl-4H,5H,6H,7H-pyrido[3,4-d][1,3]oxazol-5-yl}-4-(2,5-difluorophenyl)butan-1-one | oxazolopiperidine 77 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C19H21F2N3O2 |
|---|
| Mol. Mass. | 361.3857 |
|---|
| SMILES | N[C@@H](CC(=O)N1CCc2oc(nc2C1)C1CC1)Cc1cc(F)ccc1F |r| |
|---|
| Structure | 
|
|---|
Search and Browse
