Search and Browse
Download
Enter Data
| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Orexin receptor type 2 | ||
| Ligand | BDBM386065 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | Measurement of Orexin Type 2 Receptor Agonist Activity | ||
| EC50 | 540±n/a nM | ||
| Citation |  Fujimoto, T; Rikimaru, K; Sugimoto, H; Matsumoto, T Substituted piperidine compound and use thereof US Patent US10287305 Publication Date 5/14/2019 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Orexin receptor type 2 | |||
| Name: | Orexin receptor type 2 | ||
| Synonyms: | HCRTR2 | Hypocretin receptor type 2 | OX2R_HUMAN | Orexin receptor type 2 (OR 2) | Orexin receptor type 2 (OR-2) | Orexin receptor type 2 (OX2) | Orexin receptor type 2 (OX2R) | Orexin receptor type 2 (OxR2) | Ox-2-R | Ox2-R | ||
| Type: | Protein | ||
| Mol. Mass.: | 50710.53 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O43614 | ||
| Residue: | 444 | ||
| Sequence: |
| ||
| BDBM386065 | |||
| n/a | |||
| Name | BDBM386065 | ||
| Synonyms: | N-((2R,3S)-2-(((cis-4- phenylcyclohexyl)oxy)methyl)- piperidin-3-yl)methanesulfonamide | US10287305, Example 3 | US10287305, Example 333 | US10508083, Example 333 | US11292766, Example 333 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C19H30N2O3S | ||
| Mol. Mass. | 366.518 | ||
| SMILES | CS(=O)(=O)N[C@H]1CCCN[C@H]1CO[C@H]1CC[C@H](CC1)c1ccccc1 |r,wU:16.20,13.13,10.11,5.4,(6.99,-1.33,;5.9,-.24,;5.5,1.25,;6.99,.85,;4.41,-.64,;4.01,-2.12,;5.1,-3.21,;4.7,-4.7,;3.21,-5.1,;2.12,-4.01,;2.52,-2.52,;1.43,-1.43,;-.05,-1.83,;-1.14,-.74,;-2.63,-1.14,;-3.72,-.05,;-3.32,1.43,;-1.83,1.83,;-.74,.74,;-4.41,2.52,;-4.01,4.01,;-5.1,5.1,;-6.59,4.7,;-6.99,3.21,;-5.9,2.12,)| | ||
| Structure | 
| ||