Reaction Details | |||
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Report a problem with these data | |||
Target | Orexin receptor type 2 | ||
Ligand | BDBM386162 | ||
Substrate/Competitor | n/a | ||
Meas. Tech. | Measurement of Orexin Type 2 Receptor Agonist Activity | ||
EC50 | 0.120±n/a nM | ||
Citation | Fujimoto, T; Rikimaru, K; Sugimoto, H; Matsumoto, T Substituted piperidine compound and use thereof US Patent US10287305 Publication Date 5/14/2019 | ||
More Info.: | Get all data from this article, Assay Method | ||
Orexin receptor type 2 | |||
Name: | Orexin receptor type 2 | ||
Synonyms: | HCRTR2 | Hypocretin receptor type 2 | OX2R_HUMAN | Orexin receptor type 2 (OR 2) | Orexin receptor type 2 (OR-2) | Orexin receptor type 2 (OX2) | Orexin receptor type 2 (OX2R) | Orexin receptor type 2 (OxR2) | Ox-2-R | Ox2-R | ||
Type: | Protein | ||
Mol. Mass.: | 50710.53 | ||
Organism: | Homo sapiens (Human) | ||
Description: | O43614 | ||
Residue: | 444 | ||
Sequence: |
| ||
BDBM386162 | |||
n/a | |||
Name | BDBM386162 | ||
Synonyms: | US10287305, Example 117 | US10508083, Example 117 | US11292766, Example 117 | cis-N-ethyl-2-(((cis-4-(2- fluorophenyl)cyclohexyl)oxy)-methyl)- 3-((methylsulfonyl)amino)piperidine-1- carboxamide | ||
Type | Small organic molecule | ||
Emp. Form. | C22H34FN3O4S | ||
Mol. Mass. | 455.586 | ||
SMILES | CCNC(=O)N1CCC[C@H](NS(C)(=O)=O)[C@@H]1CO[C@H]1CC[C@H](CC1)c1ccccc1F |r,wU:21.25,18.18,15.16,9.9,(-2.67,-3.47,;-1.33,-4.23,;,-3.47,;1.33,-4.23,;1.33,-5.78,;2.67,-3.47,;4,-4.23,;5.33,-3.47,;5.33,-1.93,;4,-1.15,;4,.38,;5.33,1.15,;6.67,.38,;4,1.93,;6.42,2.24,;2.67,-1.93,;1.33,-1.15,;1.33,.38,;,1.15,;-1.33,.38,;-2.67,1.15,;-2.67,2.69,;-1.33,3.47,;,2.69,;-4,3.46,;-5.33,2.69,;-6.67,3.46,;-6.67,5,;-5.33,5.78,;-4,5,;-2.67,5.77,)| | ||
Structure |