| Reaction Details |
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 | Report a problem with these data |
| Target | Bromodomain-containing protein 4 [44-167] |
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| Ligand | BDBM259894 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | in vitro kinase inhibition assay |
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| IC50 | 646±n/a nM |
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| Citation |  Durden, DL; Morales, GA; Garlich, JR Thienopyranones as kinase and epigenetic inhibitors US Patent US10308662 Publication Date 6/4/2019 |
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| More Info.: | Get all data from this article, Assay Method |
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| Bromodomain-containing protein 4 [44-167] |
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| Name: | Bromodomain-containing protein 4 [44-167] |
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| Synonyms: | BRD4 | BRD4 bromodomain 1 | BRD4_HUMAN | Brd4-1 | HUNK1 |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 14738.39 |
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| Organism: | Homo sapiens (Human) |
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| Description: | O60885[44-167] |
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| Residue: | 124 |
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| Sequence: | NPPPPETSNPNKPKRQTNQLQYLLRVVLKTLWKHQFAWPFQQPVDAVKLNLPDYYKIIKT
PMDMGTIKKRLENNYYWNAQECIQDFNTMFTNCYIYNKPGDDIVLMAEALEKLFLQKINE
LPTE
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| BDBM259894 |
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| n/a |
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| Name | BDBM259894 |
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| Synonyms: | US10308662, Compound 135 | US9505780, 135 |
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| Type | Small organic molecule |
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| Emp. Form. | C25H23N3O4S |
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| Mol. Mass. | 461.533 |
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| SMILES | Cc1cccc(NC(=O)Nc2cccc(c2)-c2csc3c2oc(cc3=O)N2CCOCC2)c1 |
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| Structure | 
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