| Reaction Details |
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 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] B |
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| Ligand | BDBM36478 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | MAO-B Enzymatic Assay |
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| IC50 | 1±0.0 nM |
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| Citation |  Kokel, D; Bryan, J; Laggner, C; White, R; Cheung, CY; Mateus, R; Healey, D; Kim, S; Werdich, AA; Haggarty, SJ; Macrae, CA; Shoichet, B; Peterson, RT Rapid behavior-based identification of neuroactive small molecules in the zebrafish. Nat Chem Biol6:231-237 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Amine oxidase [flavin-containing] B |
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| Name: | Amine oxidase [flavin-containing] B |
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| Synonyms: | AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB) |
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| Type: | Protein |
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| Mol. Mass.: | 58768.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P27338 |
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| Residue: | 520 |
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| Sequence: | MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY
VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR
TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV
SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ
TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY
YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER
LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR
IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT
FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
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| BDBM36478 |
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| n/a |
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| Name | BDBM36478 |
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| Synonyms: | 6-Oxo-7,8,9,10-tetrahydrobenzo[c]chromen-3-yl benzoate | MAG-1 |
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| Type | Small organic molecule |
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| Emp. Form. | C20H16O4 |
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| Mol. Mass. | 320.3386 |
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| SMILES | O=C(Oc1ccc2c3CCCCc3c(=O)oc2c1)c1ccccc1 |
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| Structure | 
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