| Reaction Details |
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 | Report a problem with these data |
| Target | Amine oxidase [flavin-containing] B |
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| Ligand | BDBM256641 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | MAO-B Inhibitory Assay |
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| pH | 7.5±n/a |
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| Temperature | 298.15±n/a K |
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| IC50 | >100000±n/a nM |
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| Comments | extracted |
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| Citation |  Matsumoto, S; Hattori, Y; Toyofuku, M; Morimoto, S; Kojima, T; Kaku, T; Ito, M Cyclopropanamine compound and use thereof US Patent US9714241 Publication Date 7/25/2017 |
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| More Info.: | Get all data from this article, Assay Method |
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| |
| Amine oxidase [flavin-containing] B |
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| Name: | Amine oxidase [flavin-containing] B |
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| Synonyms: | AOFB_HUMAN | MAO-B | MAOB | Monoamine oxidase type B | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAO B) | Monoamine oxidase type B (MAOB) |
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| Type: | Protein |
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| Mol. Mass.: | 58768.76 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P27338 |
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| Residue: | 520 |
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| Sequence: | MSNKCDVVVVGGGISGMAAAKLLHDSGLNVVVLEARDRVGGRTYTLRNQKVKYVDLGGSY
VGPTQNRILRLAKELGLETYKVNEVERLIHHVKGKSYPFRGPFPPVWNPITYLDHNNFWR
TMDDMGREIPSDAPWKAPLAEEWDNMTMKELLDKLCWTESAKQLATLFVNLCVTAETHEV
SALWFLWYVKQCGGTTRIISTTNGGQERKFVGGSGQVSERIMDLLGDRVKLERPVIYIDQ
TRENVLVETLNHEMYEAKYVISAIPPTLGMKIHFNPPLPMMRNQMITRVPLGSVIKCIVY
YKEPFWRKKDYCGTMIIDGEEAPVAYTLDDTKPEGNYAAIMGFILAHKARKLARLTKEER
LKKLCELYAKVLGSLEALEPVHYEEKNWCEEQYSGGCYTTYFPPGILTQYGRVLRQPVDR
IYFAGTETATHWSGYMEGAVEAGERAAREILHAMGKIPEDEIWQSEPESVDVPAQPITTT
FLERHLPSVPGLLRLIGLTTIFSATALGFLAHKRGLLVRV
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| BDBM256641 |
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| n/a |
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| Name | BDBM256641 |
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| Synonyms: | US10053456, 20 | US10414761, Example 20 | US10968213, Example 20 | US9487511, 20 | US9718814, 20 | US9920047, 20 |
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| Type | Small organic molecule |
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| Emp. Form. | C18H24N4O2S2 |
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| Mol. Mass. | 392.539 |
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| SMILES | Cc1nnc(NC(=O)c2cc(C3CC3NCC3CCOCC3)c(C)s2)s1 |
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| Structure | 
|
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