Reaction Details |
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Target | Procathepsin L |
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Ligand | BDBM55135 |
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Substrate/Competitor | n/a |
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Meas. Tech. | QFRET-based counterscreen for inhibitors of PFM18AAP: biochemical high throughput dose response assay for inhibitors of the Cathepsin L proteinase (CTSL1). |
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IC50 | >59642±n/a nM |
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Citation | PubChem, PC QFRET-based counterscreen for inhibitors of PFM18AAP: biochemical high throughput dose response assay for inhibitors of the Cathepsin L proteinase (CTSL1). PubChem Bioassay(2009)[AID] |
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More Info.: | Get all data from this article, Solution Info, Assay Method |
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Procathepsin L |
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Name: | Procathepsin L |
Synonyms: | CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein |
Type: | Enzyme |
Mol. Mass.: | 37557.19 |
Organism: | Homo sapiens (Human) |
Description: | Purchased from Calbiochem (San Diego, CA). |
Residue: | 333 |
Sequence: | MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIE
LHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDW
REKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNG
GLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVA
TVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKN
SWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
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BDBM55135 |
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n/a |
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Name | BDBM55135 |
Synonyms: | 2-bromanyl-N-(1,2,4-triazol-4-ylcarbamothioyl)benzamide | 2-bromo-N-(1,2,4-triazol-4-ylcarbamothioyl)benzamide | 2-bromo-N-(1,2,4-triazol-4-ylthiocarbamoyl)benzamide | 2-bromo-N-[sulfanylidene-(1,2,4-triazol-4-ylamino)methyl]benzamide | MLS000392642 | SMR000261511 | cid_2375959 |
Type | Small organic molecule |
Emp. Form. | C10H8BrN5OS |
Mol. Mass. | 326.172 |
SMILES | Brc1ccccc1C(=O)NC(=S)Nn1cnnc1 |
Structure |
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