| Reaction Details |
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 | Report a problem with these data |
| Target | Mitochondrial import inner membrane translocase subunit TIM23 |
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| Ligand | BDBM78181 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of uHTS small molecule inhibitors of tim10-1: a luminescent tim23-1 yeast counterscreen. |
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| IC50 | 7940±n/a nM |
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| Citation |  PubChem, PC Dose Response confirmation of uHTS small molecule inhibitors of tim10-1: a luminescent tim23-1 yeast counterscreen. PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| Mitochondrial import inner membrane translocase subunit TIM23 |
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| Name: | Mitochondrial import inner membrane translocase subunit TIM23 |
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| Synonyms: | MAS6 | MIM23 | MPI3 | TIM23 | TIM23_YEAST | TPA: Essential component of the Translocase of the Inner Mitochondrial membrane (TIM23 complex) |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 23245.32 |
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| Organism: | Saccharomyces cerevisiae S288c |
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| Description: | gi_285814664 |
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| Residue: | 222 |
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| Sequence: | MSWLFGDKTPTDDANAAVGGQDTTKPKELSLKQSLGFEPNINNIISGPGGMHVDTARLHP
LAGLDKGVEYLDLEEEQLSSLEGSQGLIPSRGWTDDLCYGTGAVYLLGLGIGGFSGMMQG
LQNIPPNSPGKLQLNTVLNHITKRGPFLGNNAGILALSYNIINSTIDALRGKHDTAGSIG
AGALTGALFKSSKGLKPMGYSSAMVAAACAVWCSVKKRLLEK
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| BDBM78181 |
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| n/a |
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| Name | BDBM78181 |
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| Synonyms: | (E)-3-(3-Benzotriazol-1-ylmethyl-4-methoxy-phenyl)-1-phenyl-propenone | (E)-3-[3-(1-benzotriazolylmethyl)-4-methoxyphenyl]-1-phenyl-2-propen-1-one | (E)-3-[3-(benzotriazol-1-ylmethyl)-4-methoxy-phenyl]-1-phenyl-prop-2-en-1-one | (E)-3-[3-(benzotriazol-1-ylmethyl)-4-methoxyphenyl]-1-phenylprop-2-en-1-one | MLS000589828 | SMR000217110 | cid_6184004 |
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| Type | Small organic molecule |
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| Emp. Form. | C23H19N3O2 |
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| Mol. Mass. | 369.4159 |
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| SMILES | COc1ccc(\C=C\C(=O)c2ccccc2)cc1Cn1nnc2ccccc12 |
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| Structure | 
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