| Reaction Details |
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 | Report a problem with these data |
| Target | DNA dC->dU-editing enzyme APOBEC-3G |
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| Ligand | BDBM80124 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | Dose Response confirmation of small molecule APOBEC3G DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay |
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| Temperature | 298.15±n/a K |
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| IC50 | 15800±n/a nM |
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| Comments | extracted |
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| Citation |  PubChem, PC Dose Response confirmation of small molecule APOBEC3G DNA Deaminase Inhibitors via a fluorescence-based single-stranded DNA deaminase assay PubChem Bioassay(2011)[AID] |
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| More Info.: | Get all data from this article, Solution Info, Assay Method |
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| DNA dC->dU-editing enzyme APOBEC-3G |
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| Name: | DNA dC->dU-editing enzyme APOBEC-3G |
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| Synonyms: | ABC3G_HUMAN | APOBEC3G |
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| Type: | Enzyme Catalytic Domain |
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| Mol. Mass.: | 46419.54 |
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| Organism: | Homo sapiens (Human) |
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| Description: | gi_13399304 |
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| Residue: | 384 |
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| Sequence: | MKPHFRNTVERMYRDTFSYNFYNRPILSRRNTVWLCYEVKTKGPSRPPLDAKIFRGQVYS
ELKYHPEMRFFHWFSKWRKLHRDQEYEVTWYISWSPCTKCTRDMATFLAEDPKVTLTIFV
ARLYYFWDPDYQEALRSLCQKRDGPRATMKIMNYDEFQHCWSKFVYSQRELFEPWNNLPK
YYILLHIMLGEILRHSMDPPTFTFNFNNEPWVRGRHETYLCYEVERMHNDTWVLLNQRRG
FLCNQAPHKHGFLEGRHAELCFLDVIPFWKLDLDQDYRVTCFTSWSPCFSCAQEMAKFIS
KNKHVSLCIFTARIYDDQGRCQEGLRTLAEAGAKISIMTYSEFKHCWDTFVDHQGCPFQP
WDGLDEHSQDLSGRLRAILQNQEN
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| BDBM80124 |
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| n/a |
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| Name | BDBM80124 |
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| Synonyms: | 2-(5-Thioxo-4,5-dihydro-[1,3,4]thiadiazol-2-ylsulfanyl)-propionic acid methyl ester | 2-[(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)thio]propanoic acid methyl ester | 2-[(2-thioxo-3H-1,3,4-thiadiazol-5-yl)thio]propionic acid methyl ester | MLS000554705 | SMR000146822 | cid_3742133 | methyl 2-[(2-sulfanylidene-3H-1,3,4-thiadiazol-5-yl)sulfanyl]propanoate |
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| Type | Small organic molecule |
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| Emp. Form. | C6H8N2O2S3 |
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| Mol. Mass. | 236.335 |
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| SMILES | COC(=O)C(C)Sc1nnc(S)s1 |
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| Structure | 
|
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