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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Tyrosine-protein kinase JAK2 | ||
| Ligand | BDBM270877 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | JAK Enzyme Assay | ||
| IC50 | >10000±n/a nM | ||
| Citation |  Gauvry, N; Tahtaoui, C; Furet, P; Ducray, P Compounds US Patent US10059709 Publication Date 8/28/2018 | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Tyrosine-protein kinase JAK2 | |||
| Name: | Tyrosine-protein kinase JAK2 | ||
| Synonyms: | JAK-2 | JAK2 | JAK2_HUMAN | Janus kinase 2 | Janus kinase 2 (JAK2) | Janus kinase 2 (a protein tyrosine kinase) | ||
| Type: | Protein | ||
| Mol. Mass.: | 130684.68 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | O60674 | ||
| Residue: | 1132 | ||
| Sequence: |
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| BDBM270877 | |||
| n/a | |||
| Name | BDBM270877 | ||
| Synonyms: | US10059709, 23 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C18H25N5O2S | ||
| Mol. Mass. | 375.488 | ||
| SMILES | CNS(=O)(=O)C[C@H]1CC[C@@H](CC1)Nc1nc(N)ncc1-c1ccccc1 |r,wU:9.12,wD:6.5,(7.34,2.8,;6,2.03,;4.67,2.8,;5.44,4.13,;3.9,1.46,;3.33,3.57,;2,2.8,;.67,3.57,;-.67,2.8,;-.67,1.26,;.67,.49,;2,1.26,;-2,.49,;-2,-1.05,;-.67,-1.82,;-.67,-3.36,;.67,-4.13,;-2,-4.13,;-3.33,-3.36,;-3.33,-1.82,;-4.67,-1.05,;-4.67,.49,;-6,1.26,;-7.34,.49,;-7.34,-1.05,;-6,-1.82,)| | ||
| Structure | 
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