| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Neuromedin-U receptor 2 |
|---|
| Ligand | BDBM50262109 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEBML_1696564 |
|---|
| EC50 | 3.8±n/a nM |
|---|
| Citation |  Nishizawa, N; Kanematsu-Yamaki, Y; Funata, M; Nagai, H; Shimizu, A; Fujita, H; Sakamoto, J; Takekawa, S; Asami, T A potent neuromedin U receptor 2-selective alkylated peptide. Bioorg Med Chem Lett27:4626-4629 (2017) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Neuromedin-U receptor 2 |
|---|
| Name: | Neuromedin-U receptor 2 |
|---|
| Synonyms: | G-protein coupled receptor FM-4 | G-protein coupled receptor TGR-1 | NMU-R2 | NMU2R | NMU2R | NMUR2 | NMUR2_HUMAN | Neuromedin-U receptor 2 | TGR1 |
|---|
| Type: | PROTEIN |
|---|
| Mol. Mass.: | 47710.86 |
|---|
| Organism: | Homo sapiens (Human) |
|---|
| Description: | ChEMBL_103075 |
|---|
| Residue: | 415 |
|---|
| Sequence: | MSGMEKLQNASWIYQQKLEDPFQKHLNSTEEYLAFLCGPRRSHFFLPVSVVYVPIFVVGV
IGNVLVCLVILQHQAMKTPTNYYLFSLAVSDLLVLLLGMPLEVYEMWRNYPFLFGPVGCY
FKTALFETVCFASILSITTVSVERYVAILHPFRAKLQSTRRRALRILGIVWGFSVLFSLP
NTSIHGIKFHYFPNGSLVPGSATCTVIKPMWIYNFIIQVTSFLFYLLPMTVISVLYYLMA
LRLKKDKSLEADEGNANIQRPCRKSVNKMLFVLVLVFAICWAPFHIDRLFFSFVEEWSES
LAAVFNLVHVVSGVFFYLSSAVNPIIYNLLSRRFQAAFQNVISSFHKQWHSQHDPQLPPA
QRNIFLTECHFVELTEDIGPQFPCQSSMHNSHLPAALSSEQMSRTNYQSFHFNKT
|
|
|
|---|
| BDBM50262109 |
|---|
| n/a |
|---|
| Name | BDBM50262109 |
|---|
| Synonyms: | CHEMBL4080881 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C96H151N17O22 |
|---|
| Mol. Mass. | 1895.3268 |
|---|
| SMILES | CCCCCCCCCCCCCCCC(=O)NCCOCCOCCOCCOCCC(=O)NCCOCCOCCOCCOCCC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](Cc1ccc2ccccc2c1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CCCNC(N)=N)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CC(N)=O)C(O)=O |r| |
|---|
| Structure | 
|
|---|
Search and Browse
