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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Steroid 17-alpha-hydroxylase/17,20 lyase | ||
| Ligand | BDBM50014458 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEBML_52085 | ||
| IC50 | 3000±n/a nM | ||
| Citation |  McCague, R; Rowlands, MG; Barrie, SE; Houghton, J Inhibition of enzymes of estrogen and androgen biosynthesis by esters of 4-pyridylacetic acid. J Med Chem33:3050-5 (1990) [PubMed] | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Steroid 17-alpha-hydroxylase/17,20 lyase | |||
| Name: | Steroid 17-alpha-hydroxylase/17,20 lyase | ||
| Synonyms: | CP17A_RAT | Cyp17 | Cyp17a1 | Cytochrome P450 17,20 lyase | Cytochrome P450 17A1 | Cytochrome P450-C17 | Steroid 17-alpha-hydroxylase/17,20 lyase | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 57255.68 | ||
| Organism: | Rattus norvegicus (Rat) | ||
| Description: | P11715 | ||
| Residue: | 507 | ||
| Sequence: |
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| BDBM50014458 | |||
| n/a | |||
| Name | BDBM50014458 | ||
| Synonyms: | CHEMBL102884 | Pyridin-4-yl-acetic acid 4-tert-butyl-cyclohexyl ester | ||
| Type | Small organic molecule | ||
| Emp. Form. | C17H25NO2 | ||
| Mol. Mass. | 275.3859 | ||
| SMILES | CC(C)(C)C1CCC(CC1)OC(=O)Cc1ccncc1 |(-2.68,-8.66,;-1.35,-7.89,;-1.33,-6.35,;-.95,-9.39,;-.02,-8.68,;-.02,-10.22,;1.31,-11,;2.64,-10.23,;2.64,-8.69,;1.33,-7.92,;3.97,-11,;5.3,-10.23,;5.3,-8.69,;6.63,-11,;7.98,-10.23,;9.31,-11,;10.65,-10.23,;10.65,-8.69,;9.31,-7.92,;7.98,-8.69,)| | ||
| Structure | 
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