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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Protein kinase C epsilon type | ||
| Ligand | BDBM50280752 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1722135 (CHEMBL4137135) | ||
| Ki | 42±n/a nM | ||
| Citation |  Ann, J; Czikora, A; Saini, AS; Zhou, X; Mitchell, GA; Lewin, NE; Peach, ML; Blumberg, PM; Lee, J ?-Arylidene Diacylglycerol-Lactones (DAG-Lactones) as Selective Ras Guanine-Releasing Protein 3 (RasGRP3) Ligands. J Med Chem61:6261-6276 (2018) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Protein kinase C epsilon type | |||
| Name: | Protein kinase C epsilon type | ||
| Synonyms: | KPCE_HUMAN | PKC epsilon | PKCE | PRKCE | Protein kinase C epsilon | Protein kinase C epsilon type | Protein kinase C, PKC; classical/novel | Protein kinase C, epsilon | nPKC-epsilon | ||
| Type: | Enzyme | ||
| Mol. Mass.: | 83680.45 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | The recombinant human PKC enzymes were produced using a baculovirus expression system in SF9 cells | ||
| Residue: | 737 | ||
| Sequence: |
| ||
| BDBM50280752 | |||
| n/a | |||
| Name | BDBM50280752 | ||
| Synonyms: | CHEMBL4161221 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C27H35NO5 | ||
| Mol. Mass. | 453.5705 | ||
| SMILES | Cn1cc(\C=C2/CC(CO)(COC(=O)C3CCC(CC3)C(C)(C)C)OC2=O)c2ccccc12 |(33.76,-11.61,;33.34,-10.13,;34.29,-8.91,;33.42,-7.64,;34.21,-6.31,;33.45,-4.98,;31.91,-4.98,;31.43,-3.51,;30.09,-4.27,;30.08,-5.81,;30.1,-2.73,;28.76,-3.49,;27.43,-2.71,;27.44,-1.17,;26.09,-3.48,;24.75,-2.69,;23.41,-3.45,;23.4,-5,;24.73,-5.78,;26.08,-5.02,;22.06,-5.75,;20.74,-4.98,;22.05,-7.29,;20.73,-6.51,;32.68,-2.6,;33.93,-3.51,;35.39,-3.04,;31.95,-8.07,;30.66,-7.25,;29.3,-7.97,;29.25,-9.51,;30.54,-10.31,;31.89,-9.6,)| | ||
| Structure | 
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