| Reaction Details |
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 | Report a problem with these data |
| Target | G-protein coupled receptor 55 |
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| Ligand | BDBM50449587 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_1740201 (CHEMBL4155951) |
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| IC50 | >10000±n/a nM |
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| Citation |  Schoeder, CT; Kaleta, M; Mahardhika, AB; Olejarz-Maciej, A; ?a?ewska, D; Kie?-Kononowicz, K; Müller, CE Structure-activity relationships of imidazothiazinones and analogs as antagonists of the cannabinoid-activated orphan G protein-coupled receptor GPR18. Eur J Med Chem155:381-397 (2018) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| G-protein coupled receptor 55 |
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| Name: | G-protein coupled receptor 55 |
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| Synonyms: | G protein-coupled receptor 55 | GPR55 | GPR55_HUMAN |
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| Type: | PROTEIN |
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| Mol. Mass.: | 36649.72 |
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| Organism: | Homo sapiens (Human) |
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| Description: | ChEMBL_1292265 |
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| Residue: | 319 |
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| Sequence: | MSQQNTSGDCLFDGVNELMKTLQFAVHIPTFVLGLLLNLLAIHGFSTFLKNRWPDYAATS
IYMINLAVFDLLLVLSLPFKMVLSQVQSPFPSLCTLVECLYFVSMYGSVFTICFISMDRF
LAIRYPLLVSHLRSPRKIFGICCTIWVLVWTGSIPIYSFHGKVEKYMCFHNMSDDTWSAK
VFFPLEVFGFLLPMGIMGFCCSRSIHILLGRRDHTQDWVQQKACIYSIAASLAVFVVSFL
PVHLGFFLQFLVRNSFIVECRAKQSISFFLQLSMCFSNVNCCLDVFCYYFVIKEFRMNIR
AHRPSRVQLVLQDTTISRG
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| BDBM50449587 |
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| n/a |
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| Name | BDBM50449587 |
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| Synonyms: | CHEMBL4161205 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H21ClN2O3S |
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| Mol. Mass. | 428.932 |
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| SMILES | Clc1ccc(OCCCOc2cccc(\C=C3/N=C4SCCCN4C3=O)c2)cc1 |t:17| |
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| Structure | 
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