| Reaction Details |
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 | Report a problem with these data |
| Target | Gamma-aminobutyric acid receptor subunit gamma-1 |
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| Ligand | BDBM50021189 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEBML_68602 |
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| IC50 | 250±n/a nM |
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| Citation |  Krogsgaard-Larsen, P; Nielsen, L; Falch, E; Curtis, DR GABA agonists. Resolution, absolute stereochemistry, and enantioselectivity of (S)-(+)- and (R)-(-)-dihydromuscimol. J Med Chem28:1612-7 (1985) [PubMed] |
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| More Info.: | Get all data from this article, Assay Method |
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| Gamma-aminobutyric acid receptor subunit gamma-1 |
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| Name: | Gamma-aminobutyric acid receptor subunit gamma-1 |
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| Synonyms: | Benzodiazepine receptors | Benzodiazepine receptors; peripheral & central | GABA receptor gamma-1 subunit | GBRG1_RAT | Gabrg1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 53557.84 |
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| Organism: | Rattus norvegicus |
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| Description: | ChEMBL_193817 |
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| Residue: | 465 |
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| Sequence: | MGSGKVFLFSPSLLWSQTRGVRLIFLLLTLHLGNCIDKADDEDDEDLTMNKTWVLAPKIH
EGDITQILNSLLQGYDNKLRPDIGVRPTVIETDVYVNSIGPVDPINMEYTIDIIFAQTWF
DSRLKFNSTMKVLMLNSNMVGKIWIPDTFFRNSRKSDAHWITTPNRLLRIWSDGRVLYTL
RLTINAECYLQLHNFPMDEHSCPLEFSSYGYPKNEIEYKWKKPSVEVADPKYWRLYQFAF
VGLRNSTEISHTISGDYIIMTIFFDLSRRMGYFTIQTYIPCILTVVLSWVSFWINKDAVP
ARTSLGITTVLTMTTLSTIARKSLPKVSYVTAMDLFVSVCFIFVFAALMEYGTLHYFTSN
NKGKTTRDRKLKSKTSVSPGLHAGSTLIPMNNISMPQGEDDYGYQCLEGKDCATFFCCFE
DCRTGSWREGRIHIRIAKIDSYSRIFFPTAFALFNLVYWVGYLYL
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| BDBM50021189 |
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| n/a |
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| Name | BDBM50021189 |
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| Synonyms: | 5-Aminomethyl-4,5-dihydro-isoxazol-3-ol | CHEMBL40804 |
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| Type | Small organic molecule |
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| Emp. Form. | C4H8N2O2 |
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| Mol. Mass. | 116.1185 |
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| SMILES | NC[C@H]1CC(O)=NO1 |c:5| |
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| Structure | 
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