| Reaction Details |
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 | Report a problem with these data |
| Target | Choline/ethanolaminephosphotransferase 1 |
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| Ligand | BDBM50376660 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_606314 (CHEMBL1070006) |
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| IC50 | 940±n/a nM |
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| Citation |  Smith, CJ; Ali, A; Chen, L; Hammond, ML; Anderson, MS; Chen, Y; Eveland, SS; Guo, Q; Hyland, SA; Milot, DP; Sparrow, CP; Wright, SD; Sinclair, PJ 2-Arylbenzoxazoles as CETP inhibitors: Substitution of the benzoxazole moiety. Bioorg Med Chem Lett20:346-9 (2010) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| Choline/ethanolaminephosphotransferase 1 |
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| Name: | Choline/ethanolaminephosphotransferase 1 |
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| Synonyms: | 2.7.8.1 | 2.7.8.2 | CEPT1 | CEPT1_HUMAN | Choline/ethanolaminephosphotransferase 1 | hCEPT1 |
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| Type: | PROTEIN |
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| Mol. Mass.: | 46568.68 |
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| Organism: | Homo sapiens |
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| Description: | ChEMBL_117345 |
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| Residue: | 416 |
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| Sequence: | MSGHRSTRKRCGDSHPESPVGFGHMSTTGCVLNKLFQLPTPPLSRHQLKRLEEHRYQSAG
RSLLEPLMQGYWEWLVRRVPSWIAPNLITIIGLSINICTTILLVFYCPTATEQAPLWAYI
ACACGLFIYQSLDAIDGKQARRTNSSSPLGELFDHGCDSLSTVFVVLGTCIAVQLGTNPD
WMFFCCFAGTFMFYCAHWQTYVSGTLRFGIIDVTEVQIFIIIMHLLAVIGGPPFWQSMIP
VLNIQMKIFPALCTVAGTIFSCTNYFRVIFTGGVGKNGSTIAGTSVLSPFLHIGSVITLA
AMIYKKSAVQLFEKHPCLYILTFGFVSAKITNKLVVAHMTKSEMHLHDTAFIGPALLFLD
QYFNSFIDEYIVLWIALVFSFFDLIRYCVSVCNQIASHLHIHVFRIKVSTAHSNHH
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| BDBM50376660 |
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| n/a |
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| Name | BDBM50376660 |
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| Synonyms: | CHEMBL261273 |
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| Type | Small organic molecule |
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| Emp. Form. | C22H17N3O5 |
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| Mol. Mass. | 403.3875 |
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| SMILES | Cc1ccccc1OCC(=O)Nc1ccc(cc1)-c1nc2cc(ccc2o1)[N+]([O-])=O |
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| Structure | 
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