Reaction Details |
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Target | Integrase |
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Ligand | BDBM50484880 |
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Substrate/Competitor | n/a |
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Meas. Tech. | ChEMBL_809660 (CHEMBL2015879) |
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IC50 | 100±n/a nM |
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Citation | Agapkina, J; Zatsepin, T; Knyazhanskaya, E; Mouscadet, JF; Gottikh, M Structure-Activity Relationship Studies of HIV-1 Integrase Oligonucleotide Inhibitors. ACS Med Chem Lett2:532-7 (2011) [PubMed] Article |
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More Info.: | Get all data from this article, Assay Method |
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Integrase |
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Name: | Integrase |
Synonyms: | pol |
Type: | PROTEIN |
Mol. Mass.: | 32203.43 |
Organism: | Human immunodeficiency virus 1 |
Description: | ChEMBL_106649 |
Residue: | 288 |
Sequence: | FLDGIDKAQEEHEKYHSNWRAMASDFNLPPVVAKEIVASCDKCQLKGEAMHGQVDCSPGI
WQLDCTHLEGKVILVAVHVASGYIEAEVIPAETGQETAYFLLKLAGRWPVKTVHTDNGSN
FTSTTVKAACWWAGIKQEFGIPYNPQSQGVIESMNKELKKIIGQVRDQAEHLKTAVQMAV
FIHNFKRKGGIGGYSAGERIVDIIATDIQTKELQKQITKIQNFRVYYRDSRDPVWKGPAK
LLWKGEGAVVIQDNSDIKVVPRRKAKIIRDYGKQMAGDDCVASRQDED
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BDBM50484880 |
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n/a |
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Name | BDBM50484880 |
Synonyms: | CHEMBL2012010 |
Type | Small organic molecule |
Emp. Form. | C140H167Br4N36O76P11S |
Mol. Mass. | 4262.412 |
SMILES | n/a |
Structure |
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