| Reaction Details |
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 | Report a problem with these data |
| Target | 5-hydroxytryptamine receptor 6 |
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| Ligand | BDBM50492429 |
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| Substrate/Competitor | n/a |
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| Meas. Tech. | ChEMBL_970262 (CHEMBL2406665) |
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| Ki | 19460±n/a nM |
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| Citation |  Waszkielewicz, AM; Gunia, A; Szkaradek, N; Pytka, K; Siwek, A; Sata?a, G; Bojarski, AJ; Szneler, E; Marona, H Synthesis and evaluation of pharmacological properties of some new xanthone derivatives with piperazine moiety. Bioorg Med Chem Lett23:4419-23 (2013) [PubMed] Article |
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| More Info.: | Get all data from this article, Assay Method |
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| 5-hydroxytryptamine receptor 6 |
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| Name: | 5-hydroxytryptamine receptor 6 |
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| Synonyms: | 5-HT-6 | 5-HT6 | 5-hydroxytryptamine receptor 6 (5-HT-6) | 5-hydroxytryptamine receptor 6 (5-HT6R) | 5-hydroxytryptamine receptor 6 (5HT6) | 5HT6R_HUMAN | HTR6 | Serotonin (5-HT3) receptor | Serotonin 6 (5-HT6) receptor | Serotonin Receptor 6 |
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| Type: | G Protein-Coupled Receptor (GPCR) |
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| Mol. Mass.: | 46968.43 |
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| Organism: | Homo sapiens (Human) |
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| Description: | P50406 |
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| Residue: | 440 |
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| Sequence: | MVPEPGPTANSTPAWGAGPPSAPGGSGWVAAALCVVIALTAAANSLLIALICTQPALRNT
SNFFLVSLFTSDLMVGLVVMPPAMLNALYGRWVLARGLCLLWTAFDVMCCSASILNLCLI
SLDRYLLILSPLRYKLRMTPLRALALVLGAWSLAALASFLPLLLGWHELGHARPPVPGQC
RLLASLPFVLVASGLTFFLPSGAICFTYCRILLAARKQAVQVASLTTGMASQASETLQVP
RTPRPGVESADSRRLATKHSRKALKASLTLGILLGMFFVTWLPFFVANIVQAVCDCISPG
LFDVLTWLGYCNSTMNPIIYPLFMRDFKRALGRFLPCPRCPRERQASLASPSLRTSHSGP
RPGLSLQQVLPLPLPPDSDSDSDAGSGGSSGLRLTAQLLLPGEATQDPPLPTRAAAAVNF
FNIDPAEPELRPHPLGIPTN
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| BDBM50492429 |
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| n/a |
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| Name | BDBM50492429 |
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| Synonyms: | CHEMBL3215698 |
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| Type | Small organic molecule |
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| Emp. Form. | C19H22Cl4N2O2 |
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| Mol. Mass. | 452.202 |
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| SMILES | Cl.Cl.Cl.CN1CCN(Cc2cccc3c2oc2cc(Cl)ccc2c3=O)CC1 |
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| Structure | 
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