| Reaction Details |
|---|
 | Report a problem with these data |
| Target | Acetylcholinesterase |
|---|
| Ligand | BDBM9347 |
|---|
| Substrate/Competitor | n/a |
|---|
| Meas. Tech. | ChEMBL_28912 (CHEMBL638610) |
|---|
| IC50 | 1000±n/a nM |
|---|
| Citation |  Pool, WF; Woolf, TF; Reily, MD; Caprathe, BW; Emmerling, MR; Jaen, JC Identification of a 3-hydroxylated tacrine metabolite in rat and man: metabolic profiling implications and pharmacology. J Med Chem39:3014-8 (1996) [PubMed] Article |
|---|
| More Info.: | Get all data from this article, Assay Method |
|---|
| |
| Acetylcholinesterase |
|---|
| Name: | Acetylcholinesterase |
|---|
| Synonyms: | ACES_MOUSE | Acetylcholinesterase (AChE) | Acetylcholinesterase (mouse AChE) | Acetylcholinesterase precursor | Ache |
|---|
| Type: | Enzyme |
|---|
| Mol. Mass.: | 68165.65 |
|---|
| Organism: | Mus musculus (mouse) |
|---|
| Description: | n/a |
|---|
| Residue: | 614 |
|---|
| Sequence: | MRPPWYPLHTPSLAFPLLFLLLSLLGGGARAEGREDPQLLVRVRGGQLRGIRLKAPGGPV
SAFLGIPFAEPPVGSRRFMPPEPKRPWSGVLDATTFQNVCYQYVDTLYPGFEGTEMWNPN
RELSEDCLYLNVWTPYPRPASPTPVLIWIYGGGFYSGAASLDVYDGRFLAQVEGAVLVSM
NYRVGTFGFLALPGSREAPGNVGLLDQRLALQWVQENIAAFGGDPMSVTLFGESAGAASV
GMHILSLPSRSLFHRAVLQSGTPNGPWATVSAGEARRRATLLARLVGCPPGGAGGNDTEL
IACLRTRPAQDLVDHEWHVLPQESIFRFSFVPVVDGDFLSDTPEALINTGDFQDLQVLVG
VVKDEGSYFLVYGVPGFSKDNESLISRAQFLAGVRIGVPQASDLAAEAVVLHYTDWLHPE
DPTHLRDAMSAVVGDHNVVCPVAQLAGRLAAQGARVYAYIFEHRASTLTWPLWMGVPHGY
EIEFIFGLPLDPSLNYTTEERIFAQRLMKYWTNFARTGDPNDPRDSKSPQWPPYTTAAQQ
YVSLNLKPLEVRRGLRAQTCAFWNRFLPKLLSATDTLDEAERQWKAEFHRWSSYMVHWKN
QFDHYSKQERCSDL
|
|
|
|---|
| BDBM9347 |
|---|
| n/a |
|---|
| Name | BDBM9347 |
|---|
| Synonyms: | (2Z)-but-2-enedioic acid; 9-amino-1,2,3,4-tetrahydroacridin-1-ol | 9-Amino-1 ,2,3,4-tetrahydroacridin-1-ol deriv. 1a | 9-amino-1,2,3,4-tetrahydroacridin-1-ol maleate | CHEMBL23455 | CHEMBL51934 | HP-029 |
|---|
| Type | Small organic molecule |
|---|
| Emp. Form. | C13H14N2O |
|---|
| Mol. Mass. | 214.2631 |
|---|
| SMILES | Nc1c2C(O)CCCc2nc2ccccc12 |
|---|
| Structure | 
|
|---|
Search and Browse
