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| Reaction Details | |||
|---|---|---|---|
 | Report a problem with these data | ||
| Target | Serine/threonine-protein kinase D1 | ||
| Ligand | BDBM159183 | ||
| Substrate/Competitor | n/a | ||
| Meas. Tech. | ChEMBL_1808275 (CHEMBL4307634) | ||
| Ki | <0.200000±n/a nM | ||
| Citation |  Feng, JA; Lee, P; Alaoui, MH; Barrett, K; Castanedo, G; Godemann, R; McEwan, P; Wang, X; Wu, P; Zhang, Y; Harris, SF; Staben, ST Structure Based Design of Potent Selective Inhibitors of Protein Kinase D1 (PKD1). ACS Med Chem Lett10:1260-1265 (2019) [PubMed] Article | ||
| More Info.: | Get all data from this article, Assay Method | ||
| Serine/threonine-protein kinase D1 | |||
| Name: | Serine/threonine-protein kinase D1 | ||
| Synonyms: | KPCD1_HUMAN | PKD | PKD1 | PRKCM | PRKD1 | Protein kinase C mu | Protein kinase C mu type | Protein kinase C mu type (PRKD1) | Protein kinase C, PKC; classical/novel | Protein kinase D | Protein kinase D (PRKD1) | Serine/threonine-protein kinase D1 (PKD1) | nPKC-D1 | nPKC-mu | ||
| Type: | Serine/threonine-protein kinase | ||
| Mol. Mass.: | 101705.07 | ||
| Organism: | Homo sapiens (Human) | ||
| Description: | gi_115529463 | ||
| Residue: | 912 | ||
| Sequence: |
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| BDBM159183 | |||
| n/a | |||
| Name | BDBM159183 | ||
| Synonyms: | US9034866, 660 | ||
| Type | Small organic molecule | ||
| Emp. Form. | C22H20N4O3 | ||
| Mol. Mass. | 388.4192 | ||
| SMILES | Cc1cnc(o1)[C@](C)(O)C#Cc1ccc2C3CC(C3)n3cc(nc3-c2c1)C(N)=O |r,wU:6.8,wD:6.7,(8.21,.73,;6.88,-.04,;6.4,-1.51,;4.86,-1.51,;4.38,-.04,;5.63,.86,;3.05,.73,;4.38,1.5,;3.05,2.27,;1.72,-.04,;.38,-.81,;-.95,-1.58,;-.95,-3.12,;-2.28,-3.89,;-3.62,-3.12,;-4.82,-4.08,;-6.32,-3.74,;-6.99,-2.35,;-5.21,-2.35,;-6.32,-.98,;-7.23,.26,;-6.32,1.51,;-4.86,1.03,;-4.86,-.51,;-3.62,-1.58,;-2.28,-.81,;-6.72,3,;-5.63,4.08,;-8.21,3.39,)| | ||
| Structure | 
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